In the recent years characterized by the cancer immunotherapy revolution, attention has
turned to how to potentially boost and/or generate an efficient anti-tumor immune response …

Purpose: Durable clinical benefit to PD-1 blockade in non–small cell lung cancer (NSCLC)
is currently limited to a small fraction of patients, underlining the need for predictive …

Precision treatment of cancer requires knowledge on active tumor driving signal
transduction pathways to select the optimal effective targeted treatment. Currently only a …

Background It is well established that tumors are antigenic and can induce an immune
response by the host, entailing lymphocytic infiltration of the tumor and surrounding stroma …

Objective Oesophageal cancer (OEC) is an aggressive disease with a poor survival rate.
Prognostic markers are thus urgently needed. Due to the demonstrated prognostic value of …

Carcinogenesis is a complex multi-step process which reflects genetic alterations that drive
the progressive transformation of normal human cells into highly malignant derivatives. 1 …