[HTML][HTML] Fighting COVID-19: A quick review of diagnoses, therapies, and vaccines

HI Shih, CJ Wu, YF Tu, CY Chi - Biomedical journal, 2020 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) pandemic caused by a novel
coronavirus, SARS-CoV-2, has infected more than 22 million individuals and resulted in …

A century of BCG: Impact on tuberculosis control and beyond

A Ahmed, S Rakshit, V Adiga, M Dias… - Immunological …, 2021 - Wiley Online Library
BCG turns 100 this year and while it might not be the perfect vaccine, it has certainly
contributed significantly towards eradication and prevention of spread of tuberculosis (TB) …

BCG as a case study for precision vaccine development: lessons from vaccine heterogeneity, trained immunity, and immune ontogeny

A Angelidou, J Diray-Arce, MG Conti… - Frontiers in …, 2020 - frontiersin.org
Vaccines have been traditionally developed with the presumption that they exert identical
immunogenicity regardless of target population and that they provide protection solely …

The Mycobacterium tuberculosis genome at 25 years: lessons and lingering questions

BN Koleske, WR Jacobs… - The Journal of clinical …, 2023 - Am Soc Clin Investig
First achieved in 1998 by Cole et al., the complete genome sequence of Mycobacterium
tuberculosis continues to provide an invaluable resource to understand tuberculosis (TB) …

[HTML][HTML] Bacille Calmette Guérin (BCG) and new TB vaccines: Specific, cross-mycobacterial and off-target effects

N Fritschi, N Curtis, N Ritz - Paediatric respiratory reviews, 2020 - Elsevier
Abstract The Bacille Calmette Guérin (BCG) vaccine was developed over a century ago and
has become one of the most used vaccines without undergoing a modern vaccine …

A review of the BCG vaccine and other approaches toward tuberculosis eradication

T Cho, C Khatchadourian, H Nguyen… - Human vaccines & …, 2021 - Taylor & Francis
Despite aggressive eradication efforts, Tuberculosis (TB) remains a global health burden,
one that disproportionally affects poorer, less developed nations. The only vaccine approved …

[HTML][HTML] Can what have we learnt about BCG vaccination in the last 20 years help us to design a better tuberculosis vaccine?

HM Dockrell, E Butkeviciute - Vaccine, 2022 - Elsevier
The BCG vaccine will, in 2021, have been in use for 100 years. Much remains to be
understood, including the reasons for its variable efficacy against pulmonary tuberculosis in …

Bifidobacterium infantis associates with T cell immunity in human infants and is sufficient to enhance antigen-specific T cells in mice

DD Nyangahu, AU Happel, J Wendoh, A Kiravu… - Science …, 2023 - science.org
Bacille Calmette-Guerin (BCG) vaccine can elicit good TH1 responses in neonates. We
hypothesized that the pioneer gut microbiota affects vaccine T cell responses. Infants who …

Factors influencing maternal microchimerism throughout infancy and its impact on infant T cell immunity

C Balle, B Armistead, A Kiravu, X Song… - The Journal of …, 2022 - Am Soc Clin Investig
Determinants of the acquisition and maintenance of maternal microchimerism (MMc) during
infancy and the impact of MMc on infant immune responses are unknown. We examined …

A century of BCG vaccination: Immune mechanisms, animal models, non-traditional routes and implications for COVID-19

S Singh, NA Saavedra-Avila, S Tiwari… - Frontiers in …, 2022 - frontiersin.org
Bacillus Calmette-Guerin (BCG) has been used as a vaccine against tuberculosis since
1921 and remains the only currently approved vaccine for this infection. The recent …