Epidemiology of amyotrophic lateral sclerosis: an update of recent literature

E Longinetti, F Fang - Current opinion in neurology, 2019 - journals.lww.com
Provided with the increasing number of patients diagnosed with ALS and the improved
societal awareness of the disease, more resources should be allocated to the research and …

Global variation in prevalence and incidence of amyotrophic lateral sclerosis: a systematic review and meta-analysis

L Xu, T Liu, L Liu, X Yao, L Chen, D Fan, S Zhan… - Journal of …, 2020 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a global disease, which adversely affects
the life quality of patients and significantly increases the burden of families and society. We …

The amyotrophic lateral sclerosis exposome: recent advances and future directions

SA Goutman, MG Savelieff, DG Jang, J Hur… - Nature Reviews …, 2023 - nature.com
Amyotrophic lateral sclerosis (ALS) is a fatal disease of motor neuron degeneration with
typical survival of only 2–5 years from diagnosis. The causes of ALS are multifactorial …

Physical activity as an exogenous risk factor for amyotrophic lateral sclerosis: a review of the evidence

L Chapman, J Cooper-Knock, PJ Shaw - Brain, 2023 - academic.oup.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative
disorder. The only established epidemiological risk factors for ALS are male sex and …

Physical activity as risk factor in amyotrophic lateral sclerosis: a systematic review and meta-analysis

X Zheng, S Wang, J Huang, J Lin, T Yang, Y Xiao… - Journal of …, 2023 - Springer
Objective Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disorder with
rapid progression and high mortality. Physical activity (PA) has been identified as a major …

Hypothesis: etiologic and molecular mechanistic leads for sporadic neurodegenerative diseases based on experience with Western Pacific ALS/PDC

PS Spencer - Frontiers in Neurology, 2019 - frontiersin.org
Seventy years of research on Western Pacific amyotrophic lateral sclerosis and
Parkinsonism-dementia Complex (ALS/PDC) have provided invaluable data on the etiology …

Impact of comorbidities and co-medication on disease onset and progression in a large German ALS patient group

K Diekmann, M Kuzma-Kozakiewicz, M Piotrkiewicz… - Journal of …, 2020 - Springer
Introduction Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
with loss of muscle function. The pathogenesis is still unclear and the heterogeneity of ALS …

Risk factors of amyotrophic lateral sclerosis: a global meta-summary

QQ Duan, Z Jiang, WM Su, XJ Gu, H Wang… - Frontiers in …, 2023 - frontiersin.org
Background The etiology of amyotrophic lateral sclerosis (ALS) remains largely unknown.
This study aimed to summarize the relationship between ALS and its genetic and non …

[HTML][HTML] cGAS-stimulator of interferon genes signaling in central nervous system disorders

F Li, N Wang, Y Zheng, Y Luo, Y Zhang - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cytosolic nucleic acid sensors contribute to the initiation of innate immune responses by
playing a critical role in the detection of pathogens and endogenous nucleic acids. The …

Physical activity, fitness, and long-term risk of amyotrophic lateral sclerosis: A prospective cohort study

AM Vaage, HE Meyer, IK Landgraff, M Myrstad… - Neurology, 2024 - neurology.org
Background and Objectives Observational studies have demonstrated an increased
amyotrophic lateral sclerosis (ALS) risk among professional athletes in various sports. For …