The extracellular matrix is a critical component of microbial biofilms, such as dental plaque,
maintaining the spatial arrangement of cells and coordinating cellular functions throughout …

Activated neutrophils release neutrophil extracellular traps (NETs) in response to a variety of
stimuli. NETosis is driven by protein-arginine deiminase type 4, with the release of …

Biofilms are community architectures adopted by bacteria inclusive of a self-formed
extracellular matrix that protects resident bacteria from diverse environmental stresses and …

More than 75% of hospital-acquired or nosocomial urinary tract infections are initiated by
urinary catheters, which are used during the treatment of 15–25% of hospitalized patients …

Staphylococcus aureus is a major cause of nosocomial and community-acquired infections
and represents a significant burden on the healthcare system. S. aureus attachment to …

Staphylococcus aureus is a microorganism frequently associated with implant-related
infections, owing to its ability to produce biofilms. These infections are difficult to treat …

Anti-infective biomaterials need to be tailored according to the specific clinical application.
All their properties have to be tuned to achieve the best anti-infective performance together …

Biofilms are complex three-dimensional structures formed at interfaces by the vast majority
of bacteria and fungi. These robust communities have an important detrimental impact on a …

Biofilm-associated bacteria are less sensitive to antibiotics than free-living (planktonic) cells.
Furthermore, with variations in the concentration of antibiotics throughout a biofilm, microbial …

Biofilm-associated infections pose a complex problem to the medical community, in that
residence within the protection of a biofilm affords pathogens greatly increased tolerances to …