Signalling mechanisms and cellular functions of SUMO

ACO Vertegaal - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Sumoylation is an essential post-translational modification that is catalysed by a small
number of modifying enzymes but regulates thousands of target proteins in a dynamic …

SUMO: from bench to bedside

HM Chang, ETH Yeh - Physiological Reviews, 2020 - journals.physiology.org
Sentrin/small ubiquitin-like modifier (SUMO) is protein modification pathway that regulates
multiple biological processes, including cell division, DNA replication/repair, signal …

Mechanisms of deubiquitinase specificity and regulation

TET Mevissen, D Komander - Annual review of biochemistry, 2017 - annualreviews.org
Protein ubiquitination is one of the most powerful posttranslational modifications of proteins,
as it regulates a plethora of cellular processes in distinct manners. Simple …

[HTML][HTML] The post-translational modification, SUMOylation, and cancer

ZJ Han, YH Feng, BH Gu, YM Li… - … journal of oncology, 2018 - spandidos-publications.com
SUMOylation is a reversible post-translational modification which has emerged as a crucial
molecular regulatory mechanism, involved in the regulation of DNA damage repair, immune …

Function and regulation of SUMO proteases

CM Hickey, NR Wilson, M Hochstrasser - Nature reviews Molecular cell …, 2012 - nature.com
Covalent attachment of small ubiquitin-like modifier (SUMO) to proteins is highly dynamic,
and both SUMO–protein conjugation and cleavage can be regulated. Protein desumoylation …

Sumoylation: a regulatory protein modification in health and disease

A Flotho, F Melchior - Annual review of biochemistry, 2013 - annualreviews.org
Posttranslational modification with small ubiquitin-related modifier (SUMO) proteins is now
established as one of the key regulatory protein modifications in eukaryotic cells. Hundreds …

SUMO-specific proteases/isopeptidases: SENPs and beyond

A Nayak, S Müller - Genome biology, 2014 - Springer
SUMO-specific proteases/isopeptidases: SENPs and beyond | Genome Biology Skip to main
content SpringerLink Account Menu Find a journal Publish with us Track your research Search …

SUMO proteases: from cellular functions to disease

LA Claessens, ACO Vertegaal - Trends in Cell Biology, 2024 - cell.com
Posttranslational modification by small ubiquitin-like modifiers (SUMOs) is critical in
regulating diverse cellular processes including gene expression, cell cycle progression …

SUMO: a multifaceted modifier of chromatin structure and function

C Cubeñas-Potts, MJ Matunis - Developmental cell, 2013 - cell.com
A major challenge in nuclear organization is the packaging of DNA into dynamic chromatin
structures that can respond to changes in the transcriptional requirements of the cell …

Neuronal SUMOylation: mechanisms, physiology, and roles in neuronal dysfunction

JM Henley, TJ Craig, KA Wilkinson - Physiological reviews, 2014 - journals.physiology.org
Protein SUMOylation is a critically important posttranslational protein modification that
participates in nearly all aspects of cellular physiology. In the nearly 20 years since its …