In its early stages, symptoms of chronic kidney disease (CKD) are usually not apparent.
Significant reduction of the kidney function is the first obvious sign of disease. If diagnosed …

Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

Early detection and accurate monitoring of chronic kidney disease (CKD) could improve
care and retard progression to end-stage renal disease. Here, using untargeted …

Chronic kidney diseases generally lead to renal fibrosis. Despite great progress having
been made in identifying molecular mediators of fibrosis, the mechanism that governs renal …

The high-throughput, high-resolution phenotyping enabled by metabolomics has been
applied increasingly to a variety of questions in nephrology research. This article provides …

Uremic encephalopathy encompasses a wide range of central nervous system
abnormalities associated with poor kidney function occurring with either progressive chronic …

Chronic kidney disease (CKD) is a public health problem with very high prevalence and
mortality. Yet, there is a paucity of effective treatment options, partly due to insufficient …

Health risks of chronic exposure to microcystins (MCs), a family of aquatic contaminants
produced mainly by cyanobacteria, are critical yet unsolved problems. Despite a few …

Objective: Type 2 diabetes (T2D) is the primary case of chronic kidney disease (CKD).
Inflammation is associated with metabolic dysregulation in patients with T2D and CKD …

The intestinal flora serves a critical role in the development of hyperuricemia-induced
chronic kidney disease (CKD). We previously found that natural flavonol fisetin exhibited …