Memory consolidation refers to a slow process that stabilises a memory trace after initial
acquisition of novel events. The consolidation theory posits that once a memory is stored in …

The zebrafish (Danio rerio) has become a very important animal model in biomedical
research. In contrast with other models, such as mice, there has been relatively little …

Inflammatory stimulus during development increases the risk for adverse neurologic
outcome. One possible mechanism is disrupting neuronal migration. Using …

MMP‐9, a member of the matrix metalloproteinase family that degrades collagen IV and
processes chemokines and cytokines, participates in epidermal remodeling in response to …

Dexmedetomidine is an α2-adrenergic receptor agonist that exhibits a protective effect on
ischemia-reperfusion injury of the heart, kidney, and other organs. In the present study, we …

Background Peroxisome proliferator‐activated receptor (PPAR) agonists reduce voluntary
ethanol (EtOH) consumption in rat models and are promising therapeutics in the treatment …

Puerarin, a major isoflavonoid derived from the Chinese medical herb radix puerariae
(Gegen), has been reported to inhibit neuronal apoptosis and play an anti-inflammatory role …

Concerns about infectious diseases in fish used for research have risen along with the
dramatic increase in the use of fish as models in biomedical research. In addition to acute …

Background Excitatory amino acid toxicity, oxidative stress, intracellular calcium overload, as
well as inflammation and apoptosis are involved in the pathological process after cerebral …

In neurons multiple signaling pathways converge in the nucleus to regulate the expression
of genes associated with long-term structural changes of synapto-dendritic input. Of pivotal …