Problems with sleep affect a large part of the general population, with more than half of all
people in the United States reporting difficulties with sleep or insufficient sleep at various …

Psychological stressors have a prominent effect on sleep in general, and rapid eye
movement (REM) sleep in particular. Disruptions in sleep are a prominent feature, and …

There has been an increased focus on the neurological sequelae of repetitive mild traumatic
brain injury (TBI), particularly neurodegenerative syndromes, such as chronic traumatic …

Although epidemiological studies indicate that sleep-disordered breathing (SDB) such as
obstructive sleep apnea is a strong risk factor for the development of Alzheimer's disease …

Building upon the success of the Handbook of Laboratory Animal Science and completing
Volumes I and II of the Second Edition, Handbook of Laboratory Animal Science, Second …

Stress plays a critical role in the neurobiology of mood and anxiety disorders. Sleep and
circadian rhythms are affected in many of these conditions. Here we examined the effects of …

Abstract Study Objectives: Traditionally, sleep studies in mammals are performed using
electroencephalogram/electromyogram (EEG/EMG) recordings to determine sleep-wake …

Abstract Study Objectives: An ideal biomarker for sleep should change rapidly with sleep
onset, remain at a detectably differential level throughout the sleep period, and exhibit a …

Fear conditioning is thought to model anticipatory anxiety. Inbred mouse strains exhibit
different levels of reactivity to aversive environmental stimuli, which may reflect anxiety. We …

Recurrent acute and/or chronic stress can affect all vertebrate species, and can have serious
consequences. It is increasingly and widely appreciated that laboratory animals experience …