An aberrant STAT pathway is central to COVID-19

T Matsuyama, SP Kubli, SK Yoshinaga… - Cell Death & …, 2020 - nature.com
COVID-19 is caused by SARS-CoV-2 infection and characterized by diverse clinical
symptoms. Type I interferon (IFN-I) production is impaired and severe cases lead to ARDS …

Inflammatory risk factors, biomarkers and associated therapy in ischaemic stroke

CC Esenwa, MS Elkind - Nature Reviews Neurology, 2016 - nature.com
Proinflammatory conditions, including acute and chronic infections, have been associated
with an increased risk of stroke. The risk of stroke is increased by both the acute and chronic …

Inflammation-induced thrombosis: mechanisms, disease associations and management

K Aksu, A Donmez, G Keser - Current pharmaceutical design, 2012 - ingentaconnect.com
Although inflammation-induced thrombosis is a well-known entity, its pathogenesis remains
complicated. There are complex interactions between inflammation and hemostasis …

Tissue factor, blood coagulation, and beyond: an overview

AJ Chu - International journal of inflammation, 2011 - Wiley Online Library
Emerging evidence shows a broad spectrum of biological functions of tissue factor (TF). TF
classical role in initiating the extrinsic blood coagulation and its direct thrombotic action in …

The evolving role of C-reactive protein in atherothrombosis

S Devaraj, U Singh, I Jialal - Clinical chemistry, 2009 - academic.oup.com
Background: Inflammation is pivotal in all phases of atherosclerosis. Among the numerous
inflammatory biomarkers, the largest amount of published data supports a role for C-reactive …

Infections and inflammatory diseases as risk factors for venous thrombosis

YIGV Tichelaar, HJC Kluin-Nelemans… - Thrombosis and …, 2012 - thieme-connect.com
Inflammation and venous thrombosis are intertwined. Only in the recent 15 years clinical
epidemiological studies have focussed on inflammatory or infectious diseases as risk factors …

CRP and the risk of atherosclerotic events

P Calabrò, E Golia, ETH Yeh - Seminars in immunopathology, 2009 - Springer
A large body of literature supports the idea that inflammation plays a pivotal role in all
phases of atherosclerosis, from the fatty streak lesion formation to the acute coronary event …

Systemic inflammation in xenograft recipients precedes activation of coagulation

MB Ezzelarab, B Ekser, A Azimzadeh… - …, 2015 - Wiley Online Library
Background Dysregulation of coagulation is considered a major barrier against successful
pig organ xenotransplantation in non‐human primates. Inflammation is known to promote …

Inflammation and thrombosis in diabetes

K Hess, PJ Grant - Thrombosis and haemostasis, 2011 - thieme-connect.com
Patients with diabetes mellitus are at increased risk of cardiovascular morbidity and
mortality. Atherothrombosis, defined as atherosclerotic lesion disruption with superimposed …

Tissue factor and cardiovascular disease: quo vadis?

A Breitenstein, FC Tanner, TF Lüscher - Circulation Journal, 2010 - jstage.jst.go.jp
Expression of TF in ECs has been reviewed recently. 12, 13 Briefly, resting ECs express, if at
all, very little TF in vitro and in vivo. Nevertheless, upon stimulation with cytokines (tumor …