With the advent of next generation sequencing techniques a previously unknown world of
non-coding RNA molecules have been discovered. Non-coding RNA transcripts likely …

The hallmarks of cancer comprise six biological capabilities acquired during the multistep
development of human tumors. The hallmarks constitute an organizing principle for …

Abstract N 6-methyladenosine (m6A) modification is an important mechanism in miRNA
processing and maturation, but the role of its aberrant regulation in human diseases …

As angiogenesis is essential for tumor growth and metastasis, controlling tumor-associated
angiogenesis is a promising tactic in limiting cancer progression. The tumor …

Gastroenteropancreatic (GEP) neuroendocrine neoplasms (NENs) are heterogeneous
regarding site of origin, biological behavior, and malignant potential. There has been a rapid …

Kanwal R, Gupta S. Epigenetic modifications in cancer. Cancer initiation and progression is
controlled by both genetic and epigenetic events. The complexity of carcinogenesis cannot …

The conventional view of gene regulation in biology has centered around protein-coding
genes via the central dogma of DNA→ mRNA→ protein. The discovery of thousands of long …

Tumor cells metastasize to distant organs through genetic and epigenetic alterations,
including changes in microRNA (miR) expression. Here we find miR-22 triggers epithelial …

Epithelial‐to‐mesenchymal transition (EMT) is a fundamental process in development and
disease. Zinc‐finger enhancer binding (ZEB) transcription factors (ZEB1 and ZEB2) are …

Although the role of miR-200s in regulating E-cadherin expression and epithelial-to-
mesenchymal transition is well established, their influence on metastatic colonization …