A mid-pandemic night's dream: Melatonin, from harbinger of anti-inflammation to mitochondrial savior in acute and long COVID-19

IG Lempesis, VE Georgakopoulou… - International …, 2024 - spandidos-publications.com
Coronavirus disease 2019 (COVID-19), a systemic illness caused by severe acute
respiratory distress syndrome 2 (SARS-CoV-2), has triggered a worldwide pandemic with …

Light, water, and melatonin: the synergistic regulation of phase separation in dementia

D Loh, RJ Reiter - International journal of molecular sciences, 2023 - mdpi.com
The swift rise in acceptance of molecular principles defining phase separation by a broad
array of scientific disciplines is shadowed by increasing discoveries linking phase …

Assessing the antiviral potential of melatonin: A comprehensive systematic review

T Alomari, H Al‐Abdallat, R Hamamreh… - Reviews in Medical …, 2024 - Wiley Online Library
This review assesses the antiviral potential of melatonin through comprehensive analysis of
studies across human subjects, animal models, cell cultures, and in‐silico simulations. The …

[HTML][HTML] Post infectious fatigue and circadian rhythm disruption in long-COVID and other infections: a need for further research

A Livieratos, SW Lockley, S Tsiodras - eClinicalMedicine, 2025 - thelancet.com
Chronic fatigue syndrome (CFS) remains a subject of scientific research specifically with
regards to its association with infections, including the more recently described Long COVID …

Melatonin and viral infections: a review focusing on therapeutic effects and SARS-CoV-2

L Chacín-Bonilla, E Bonilla - Melatonin Research, 2024 - melatonin-research.net
Viral infections can cause serious diseases which lead to significant morbidity and mortality
of patients. In most cases, effective therapeutic approaches are lacking. Melatonin (MEL), a …

Multiple actions of melatonin in reducing viral pathophysiologies

L Chacín-Bonilla, E Bonilla - Melatonin Research, 2024 - melatonin-research.net
Viral infections lead to significant morbidity and mortality while the effective therapeutic
approaches are lacking. Melatonin (MEL)(N-acetyl-5-methoxytryptamine) is a pleiotropic …

Role of Melatonin in Viral, Bacterial and Parasitic Infections

GJM Maestroni - Biomolecules, 2024 - mdpi.com
In all mammals, the circulating pool of MLTs is synthesized in the pineal gland during the
night's darkness hours. Its main function is synchronizing the organism in the photoperiod. In …

[HTML][HTML] The mitochondria chronicles of melatonin and ATP: Guardians of phase separation

D Loh, RJ Reiter - Mitochondrial Communications, 2024 - Elsevier
Phase separation is a thermodynamic process used by all living organisms since the origin
of life to rapidly assemble and disassemble membraneless condensates in response to …

N6-腺苷甲基化修饰及其对LINE-1 的调控机制

张傲, 岑山, 李晓宇 - 遗传, 2024 - chinagene.cn
长散布元件-1 (long interspersed elements-1, LINE-1) 是现今在人类基因组中唯一具有自主转
座能力的转座子, 其转座会引起细胞基因组结构和功能的改变, 是导致多种严重疾病的重要因素 …

Chronobiological Efficacy of Combined Therapy of Pelargonium Sidoides and Melatonin in Acute and Persistent Cases of COVID-19: A Hypothetical Approach

N Taner, IC Haskologlu, E Erdag, M Mercan… - Application of Omic …, 2023 - Springer
Since the outbreak of the first SARS-CoV-2 epidemic in China, pharmacists have rapidly
engaged and developed strategies for pharmaceutical care and supply. According to the …