The balance between IL-1 and IL-1Ra in disease

WP Arend - Cytokine & growth factor reviews, 2002 - Elsevier
IL-1 is an important mediator of inflammation and tissue damage in multiple organs, both in
experimental animal models of disease and in human diseases. The IL-1 family consists of …

The history and future of T-cell depletion as graft-versus-host disease prophylaxis for allogeneic hematopoietic stem cell transplantation

VT Ho, RJ Soiffer - Blood, The Journal of the American Society …, 2001 - ashpublications.org
Despite significant progress in the past 20 years, graft-versus-host disease (GVHD) remains
a significant cause of morbidity and mortality after allogeneic hematopoietic stem cell …

Donor interleukin 1 receptor antagonist genotype associated with acute graft‐versus‐host disease in human leucocyte antigen‐matched sibling allogeneic transplants

H Cullup, AM Dickinson, GH Jackson… - British Journal of …, 2001 - Wiley Online Library
Interleukin 1 (IL‐1) is involved in various autoimmune and inflammatory diseases. IL‐1
receptor antagonist (IL‐1Ra) is the naturally occurring antagonist to IL‐1α and‐1β …

Recent advances in allogeneic hematopoietic stem-cell transplantation

SM Devine, DR Adkins, H Khoury, RA Brown… - Journal of Laboratory …, 2003 - Elsevier
The transplantation of allogeneic blood or marrow cells, abbreviated here as alloBMT, is
often the most effective treatment for a variety of advanced malignancies and life-threatening …