Hub proteins are central nodes in protein–protein interaction networks with critical
importance to all living organisms. Recently, a new group of folded hub domains, the αα …

The understanding of the mechanisms that regulate gene expression to establish
differentiation programs and determine cell lineages, is one of the major challenges in …

Background and aims CD40/CD40L signaling exerts a critical role in the development of
atherosclerosis, and microRNAs (miRNAs) are key regulators in vascular inflammation and …

Ganoderma triterpenes (GTs) are the major secondary metabolites of Ganoderma lucidum,
which is a popularly used traditional Chinese medicine for complementary cancer therapy …

TATA‐binding protein associated factor 4 (TAF4) is a subunit of the Transcription Factor IID
(TFIID) complex, a central player in transcription initiation. Other members of this multimeric …

Poly (ADP-ribos) ylation, originally described as a mechanism of DNA break repair, is now
considered as part of a complex regulatory system involved in dynamic reorganization of …

Stem cells are promising candidates for cell‐based therapies in diverse conditions including
regenerating damaged tissues, treating inflammation in virtue of sepsis, acute renal failure …

TWA1 is associated with microtubule dynamics, cell migration, nucleokinesis and
chromosome segregation. However, the role of TWA1 in gastric cancer (GC) remains …

Reprogramming of somatic cells has become a versatile tool for biomedical research and for
regenerative medicine. In the current study, we show that manipulating alternative splicing …

Histone acetylation is an important epigenic modification, modulating the development of
many tumors. However, the functions of most Histone acetylation-related genes (HARGs) …