The transcription factor CCAAT/enhancer-binding protein alpha (C/EBPα) plays a critical
role during embryogenesis and is thereafter required for homeostatic glucose metabolism …

Gankyrin plays important roles in tumorigenicity and metastasis of hepatocellular carcinoma
(HCC). We have for the first time investigated the effects of Gankyrin on glycolysis and …

Gankyrin (also known as PSMD10 or p28GANK), engages in diverse biological processes,
including cellular growth, proliferation and invasion. Several studies have demonstrated that …

Gankyrin is found in high levels in triple-negative breast cancer (TNBC) and has been
established to form a complex with the E3 ubiquitin ligase MDM2 and p53, resulting in the …

Background Gankyrin has shown to be overexpressed in human liver cancers and plays a
complex role in hepatocarcinogenesis. Panobinostat (LBH589), a new hydroxamic acid …

Gankyrin is an oncoprotein responsible for the development of numerous cancer types. It
regulates the expression levels of multiple tumor suppressor proteins (TSPs) in liver cancer; …

The aberrant expression of PSMD10 has important functions in various malignancies. This
study showed that PSMD10 was highly expressed and inversely correlated with the …

Abstract PSMB4, proteasome subunit β4, is a member of the ubiquitin-proteasome family,
and is elevated in a variety of malignancies. However, the expression level and related …

Hepatocellular carcinoma (HCC) is known as fifth common malignancies and third common
cause of cancer-related death worldwide. The identification of various mechanisms which …

Our previous research showed that Gankyrin was overexpressed in NSCLC and significantly
associated with clinicopathologic features and poor prognosis. In this study, we will explore …