Reconsidering ventilator-associated pneumonia from a new dimension of the lung microbiome

L Fernández-Barat, R López-Aladid, A Torres - EBioMedicine, 2020 - thelancet.com
Complex microbial communities that reside in the lungs, skin and gut are now appreciated
for their role in maintaining organ, tissue and immune homoeostasis. As lungs are currently …

Ventilator-associated pneumonia: the central role of transcolonization

R Soussan, C Schimpf, B Pilmis, T Degroote… - Journal of Critical …, 2019 - Elsevier
Ventilator-associated pneumonia remain frequent and serious diseases since they are
associated with considerable crude mortality. Pathophysiology is centered on modifications …

Genetic relationships between respiratory pathogens isolated from dental plaque and bronchoalveolar lavage fluid from patients in the intensive care unit undergoing …

SM Heo, EM Haase, AJ Lesse, SR Gill… - Clinical Infectious …, 2008 - academic.oup.com
Background. Ventilator-associated pneumonia (VAP) is a leading cause of morbidity and
mortality in patients hospitalized in intensive care units. Recent studies suggest that dental …

Microbial dysbiosis and mortality during mechanical ventilation: a prospective observational study

D Lamarche, J Johnstone, N Zytaruk, F Clarke… - Respiratory …, 2018 - Springer
Background Host-associated microbial communities have important roles in tissue
homeostasis and overall health. Severe perturbations can occur within these microbial …

Dental and microbiological risk factors for hospital-acquired pneumonia in non-ventilated older patients

VC Ewan, AD Sails, AWG Walls, S Rushton… - PLoS …, 2015 - journals.plos.org
Hospital acquired pneumonia (HAP) is often fatal in older patients. The mouth is the main
reservoir of infection and studies have suggested that oral hygiene interventions may …

Prevalence and Antimicrobial Resistance of Klebsiella Strains Isolated from a County Hospital in Romania

AE Ghenea, R Cioboată, AI Drocaş, EN Țieranu… - Antibiotics, 2021 - mdpi.com
The study evaluated the evolution of the incidence of infections with Klebsiella in the County
Clinical Emergency Hospital of Craiova (SCJUC), Romania. Also, we monitored antibiotic …

Bacterial infections of the oral mucosa.

G Dahlén - Periodontology 2000, 2009 - search.ebscohost.com
The article presents an overview of common bacterial infections of the oral mucosa. It
describes the microorganisms that naturally appear there, followed by a discussion of their …

Risk of an adverse event in individuals who aspirate: a review of current literature on host defenses and individual differences

PM Palmer, AH Padilla - American journal of speech-language pathology, 2022 - ASHA
Purpose: The presence of oropharyngeal dysphagia increases the likelihood of prandial
aspiration, and aspiration increases the likelihood of a dysphagia-related pulmonary …

Reducing VAP by instituting a care bundle using improvement methodology in a UK paediatric intensive care unit

J Brierley, L Highe, S Hines, G Dixon - European journal of pediatrics, 2012 - Springer
Preventing ventilator-associated pneumonia (VAP) is one of the Department of Health
Saving Lives initiatives. We describe the institution of a purpose-designed bundle of care in …

Molecular mechanisms of Staphylococcus aureus nasopharyngeal colonization

AM Edwards, RC Massey… - Molecular oral …, 2012 - Wiley Online Library
Staphylococcus aureus is responsible for a wide range of different infections ranging in
severity from mild to fatal. However, it primarily exists as a commensal organism in a number …