The role of hyaluronic acid in the design and functionalization of nanoparticles for the treatment of colorectal cancer

MC de Paula, SG Carvalho, ALP Silvestre… - Carbohydrate …, 2023 - Elsevier
Despite advances in new approaches for colorectal cancer (CRC) therapy, intravenous
chemotherapy remains one of the main treatment options; however, it has limitations …

[HTML][HTML] Applications of 3D printing in tumor treatment

J Li, D Liang, X Chen, W Sun, X Shen - Biomedical Technology, 2024 - Elsevier
As an emerging technology relevant to materials science, 3D printing technology simplifies
material production process, shortens the preparation cycle, and provides a broader space …

3D Bioprinting: An Important Tool for Tumor Microenvironment Research

Y Li, J Liu, S Xu, J Wang - International Journal of Nanomedicine, 2023 - Taylor & Francis
The tumor microenvironment plays a crucial role in cancer development and treatment.
Traditional 2D cell cultures fail to fully replicate the complete tumor microenvironment, while …

[HTML][HTML] Development of process design tools for extrusion-based bioprinting: From numerical simulations to nomograms through reduced-order modeling

F Chirianni, G Vairo, M Marino - Computer Methods in Applied Mechanics …, 2024 - Elsevier
The planning of a bioprinting procedure requires the definition of several process variables.
In extrusion-based bioprinting these are, for instance, the printing pressure, the nozzle …

[HTML][HTML] 3D printed tissue models: from hydrogels to biomedical applications

F Cadamuro, F Nicotra, L Russo - Journal of Controlled Release, 2023 - Elsevier
The development of new advanced constructs resembling structural and functional
properties of human organs and tissues requires a deep knowledge of the morphological …

[HTML][HTML] Recent advances in 3D bioprinted tumor models for personalized medicine

P Gnatowski, E Piłat, J Kucińska-Lipka, MR Saeb… - Translational …, 2023 - Elsevier
Cancerous tumors are among the most fatal diseases worldwide, claiming nearly 10 million
lives in 2020. Due to their complex and dynamic nature, modeling tumors accurately is a …

Alginate–Gelatin Self-Healing Hydrogel Produced via Static–Dynamic Crosslinking

F Cadamuro, V Ardenti, F Nicotra, L Russo - Molecules, 2023 - mdpi.com
Alginate–gelatin hydrogels mimicking extracellular matrix (ECM) of soft tissues have been
generated by static–dynamic double crosslinking, allowing fine control over the physical and …

Novel Carbohydrate Polymer‐Based Systems for Precise Drug Delivery in Colon Cancer: Improving Treatment Effectiveness With Intelligent Biodegradable Materials

N Udaipuria, S Bhattacharya - Biopolymers, 2025 - Wiley Online Library
Due to their biocompatibility, biodegradability, and controlled release, carbohydrates
polymers are crucial to targeted drug delivery systems, notably for colon cancer treatment …

Influence of extruder geometry and bio-ink type in extrusion-based bioprinting via an in silico design tool

F Chirianni, G Vairo, M Marino - Meccanica, 2024 - Springer
Planning a smooth-running and effective extrusion-based bioprinting process is a
challenging endeavor due to the intricate interplay among process variables (eg, printing …

Nanomaterials-Based Hybrid Bioink Platforms in Advancing 3D Bioprinting Technologies for Regenerative Medicine

DK Chandra, RL Reis, SC Kundu… - ACS Biomaterials …, 2024 - ACS Publications
3D bioprinting is recognized as the ultimate additive biomanufacturing technology in tissue
engineering and regeneration, augmented with intelligent bioinks and bioprinters to …