Emerging evidence that the mammalian sperm epigenome serves as a template for embryo development

A Lismer, S Kimmins - Nature communications, 2023 - nature.com
Although more studies are demonstrating that a father's environment can influence child
health and disease, the molecular mechanisms underlying non-genetic inheritance remain …

Impact of endocrine disruptors upon non-genetic inheritance

D Montjean, AS Neyroud, MG Yefimova… - International Journal of …, 2022 - mdpi.com
Similar to environmental factors, EDCs (endocrine-disrupting chemicals) can influence gene
expression without modifying the DNA sequence. It is commonly accepted that the …

Exploring the role of microbes for the management of persistent organic pollutants

M Kumar, SK Saggu, P Pratibha, SK Singh… - Journal of Environmental …, 2023 - Elsevier
Persistent organic pollutants (POPs) are chemicals which have been persisting in the
environment for many years due to their longer half-lives. POPs have gained attention over …

Predicting male fertility from the sperm methylome: application to 120 bulls with hundreds of artificial insemination records

V Costes, A Chaulot-Talmon, E Sellem, JP Perrier… - Clinical …, 2022 - Springer
Background Conflicting results regarding alterations to sperm DNA methylation in cases of
spermatogenesis defects, male infertility and poor developmental outcomes have been …

Multi-and transgenerational effects of environmental toxicants on mammalian reproduction

P Rebuzzini, G Fabozzi, D Cimadomo, FM Ubaldi… - Cells, 2022 - mdpi.com
Environmental toxicants (ETs) are an exogenous chemical group diffused in the
environment that contaminate food, water, air and soil, and through the food chain, they …

The association between long-term DDT or DDE exposures and an altered sperm epigenome—a cross-sectional study of Greenlandic Inuit and South African …

A Lismer, X Shao, MC Dumargne… - Environmental …, 2024 - ehp.niehs.nih.gov
Background: The organochlorine dichlorodiphenyltrichloroethane (DDT) is banned
worldwide owing to its negative health effects. It is exceptionally used as an insecticide for …

O-GlcNAcylation: the sweet side of epigenetics

T Dupas, B Lauzier, S McGraw - Epigenetics & Chromatin, 2023 - Springer
Histones display a wide variety of post-translational modifications, including acetylation,
methylation, and phosphorylation. These epigenetic modifications can influence chromatin …

Transgenerational impact of grand‐paternal lifetime exposures to both folic acid deficiency and supplementation on genome‐wide DNA methylation in male germ …

D Chan, L Ly, EMD Rebolledo, J Martel, M Landry… - …, 2023 - Wiley Online Library
Background DNA methylation (DNAme) erasure and reacquisition occur during prenatal
male germ cell development; some further remodeling takes place after birth during …

[HTML][HTML] Aging of common carp (Cyprinus carpio L.) sperm induced by short-term storage does not alter global DNA methylation and specific histone modifications in …

Y Cheng, SG Waghmare, S Zhang, P Vechtová… - Aquaculture, 2023 - Elsevier
Short-term storage of sperm is a useful tool to synchronize the availability of male and
female gametes for fertilization in a hatchery. Induced aging by short-term storage has been …

Exposure of Greenlandic Inuit and South African VhaVenda men to the persistent DDT metabolite is associated with an altered sperm epigenome at regions …

A Lismer, X Shao, MC Dumargne, C Lafleur, R Lambrot… - bioRxiv, 2022 - biorxiv.org
Background The persistent organochlorine dichlorodiphenyltrichloroethane (DDT) is
banned world-wide due to its negative health effects and persistence in the environment. It is …