An astonishing number of extracellular matrix glycoproteins are expressed in dynamic
patterns in the developing and adult nervous system. Neural stem cells, neurons, and glia …

Integrins are adhesion receptors that allow cells to sense and respond to
microenvironmental signals encoded by the extracellular matrix. They are crucial for the …

The cerebellum is a pre-eminent model for the study of neurogenesis and circuit assembly.
Increasing interest in the cerebellum as a participant in higher cognitive processes and as a …

More than three decades ago, basement membranes (BMs) were described as membrane-
like structures capable of isolating a cell from and connecting a cell to its environment. Since …

Integrin-linked kinase (ILK) is a multifunctional intracellular effector of cell-matrix interactions
and regulates many cellular processes, including growth, proliferation, survival …

Scientists and clinicians who study genetic alterations and disease have traditionally
described phenotypes in natural language. The considerable variation in these free-text …

Advances in neuroimaging, developmental biology and molecular genetics have increased
the understanding of developmental disorders affecting the midbrain and hindbrain, both as …

Stem cells of adult regenerative organs share a common goal but few established
conserved mechanisms. Within the neural stem cell niche of the mouse olfactory epithelium …

Integrins are cell surface receptors that form the link between extracellular matrix molecules
of the cell environment and internal cell signalling and the cytoskeleton. They are involved in …

Adhesion of cells to the surrounding extracellular matrix and to other cells is essential for
tissue integrity. In addition to this structural function, cell adhesion induces intracellular …