Francisella tularensis has been recognized as a human pathogen for almost 100 years and
is the etiological agent of the zoonotic disease tularemia. Soon after its discovery, it became …

Tularemia is a zoonosis of humans caused by infection with the facultative intracellular
bacterium Francisella tularensis. Interest in F. tularensis has increased markedly in the past …

Francisella tularensis subverts the immune system to rapidly grow within mammalian hosts,
often causing tularemia, a fatal disease. This pathogen targets the cytosol of macrophages …

The highly infectious bacterium Francisella tularensis is a facultative intracellular pathogen,
whose virulence requires proliferation inside host cells, including macrophages. Here we …

Background Francisella tularensis subspecies tularensis and holarctica are pathogenic to
humans, whereas the two other subspecies, novicida and mediasiatica, rarely cause …

Francisella tularensis has been recognized as the causative agent of tularaemia for almost a
century. Since its discovery in 1911, it has been shown to infect a wide range of hosts …

Francisella tularensis is a gram-negative pathogen that causes life-threatening infections in
humans and has potential for use as a biological weapon. The genetic basis of the F …

Background Francisella tularensis is a gram negative, facultative intracellular bacterium that
is the etiological agent of tularemia. F. novicida is closely related to F. tularensis but has low …

Francisella tularensis is a highly virulent gram-negative intracellular bacterium that causes
the zoonotic disease tularemia. Essential for its virulence is the ability to multiply within host …

Francisella tularensis (Ft) is a Gram-negative bacterium and the causative agent of
tularemia. It is well established that this organism replicates inside macrophages, but we are …