Programmed DNA elimination in the parasitic nematode Ascaris

B Estrem, J Wang - PLoS pathogens, 2023 - journals.plos.org
In most organisms, the whole genome is maintained throughout the life span. However,
exceptions occur in some species where the genome is reduced during development …

SL trans-splicing: easy come or easy go?

KEM Hastings - Trends in genetics, 2005 - cell.com
Is spliced-leader (SL) trans-splicing an ancestral eukaryotic characteristic that has been lost
in multiple lineages, or did it arise independently in the various phyla in which it occurs …

Spliced leader RNA trans-splicing in dinoflagellates

H Zhang, Y Hou, L Miranda… - Proceedings of the …, 2007 - National Acad Sciences
Through the analysis of hundreds of full-length cDNAs from fifteen species representing all
major orders of dinoflagellates, we demonstrate that nuclear-encoded mRNAs in all species …

Trans‐splicing

EL Lasda, T Blumenthal - Wiley Interdisciplinary Reviews: RNA, 2011 - Wiley Online Library
Trans‐splicing is the joining together of portions of two separate pre‐mRNA molecules. The
two distinct categories of spliceosomal trans‐splicing are genic trans‐splicing, which joins …

mRNA 5′-leader trans-splicing in the chordates

AE Vandenberghe, TH Meedel… - Genes & …, 2001 - genesdev.cshlp.org
We report the discovery of mRNA 5′-leader trans-splicing (SL trans-splicing) in the
chordates. In the ascidian protochordate Ciona intestinalis, the mRNAs of at least seven …

A phylogeny of Caenorhabditis reveals frequent loss of introns during nematode evolution

S Cho, SW Jin, A Cohen, RE Ellis - Genome research, 2004 - genome.cshlp.org
Since introns were discovered 26 years ago, people have wondered how changes in
intron/exon structure occur, and what role these changes play in evolution. To answer these …

Nematoda: genes, genomes and the evolution of parasitism

ML Blaxter - Adv Parasitol, 2003 - books.google.com
Nematodes are remarkably successful, both as free-living organisms and as parasites. The
diversity of parasitic lifestyles displayed by nematodes, and the diversity of hosts used …

Characterization of a Novel Serotonin Receptor from Caenorhabditis elegans Cloning and Expression of Two Splice Variants

FF Hamdan, MD Ungrin, M Abramovitz… - Journal of …, 1999 - Wiley Online Library
Serotonin [5‐hydroxytryptamine (5‐HT)] modulates feeding activity, egg‐laying, and mating
behavior in the free‐living nematode, Caenorhabditis elegans. We have cloned a novel …

Trans-spliced leader addition to mRNAs in a cnidarian

NA Stover, RE Steele - … of the National Academy of Sciences, 2001 - National Acad Sciences
A search of databases with the sequence from the 5′ untranslated region of a Hydra cDNA
clone encoding a receptor protein-tyrosine kinase revealed that a number of Hydra cDNAs …

mRNA Trans-splicing in the Human Parasitic CestodeEchinococcus multilocularis

K Brehm, K Jensen, M Frosch - Journal of Biological Chemistry, 2000 - ASBMB
An identical 36-nucleotide exon was identified at the 5′ termini of different mRNAs from the
cestodeEchinococcus multilocularis. We provide evidence that this exon constitutes a new …