Organoids are established through in vitro 3D culture, and they can mimic the structure and
physiological functions of organs or tissues in vivo. Organoids have attracted much attention …

In the last decades three-dimensional (3D) in vitro cancer models have been proposed as a
bridge between bidimensional (2D) cell cultures and in vivo animal models, the gold …

One major challenge associated with lung cancer organoids (LCOs) is their predominant
derivation from surgical specimens of patients with early-stage lung cancer. However …

Microfluidic technologies have garnered significant attention due to their ability to rapidly
process samples and precisely manipulate fluids in assays, making them an attractive …

For large libraries of small molecules, exhaustive combinatorial chemical screens become
infeasible to perform when considering a range of disease models, assay conditions, and …

Cancer remains a severe public health burden worldwide. One of the challenges hampering
effective cancer therapy is that the existing cancer models hardly recapitulate the tumor …

Retinal degeneration (RD), a group of diseases leading to irreversible vision loss, is
characterised by retinal pigment epithelium (RPE) or retinal neuron damage and loss. With …

Patient‐derived organoids (PDOs) developed ex vivo and in vitro are increasingly used for
therapeutic screening. They provide a more physiologically relevant model for drug …

Despite advancements in treatment protocols, cancer is one of the leading cause of deaths
worldwide. Therefore, there is a need to identify newer and personalized therapeutic targets …

Tumor organoids have been pushed forward as advanced model systems for in vitro
oncology drug testing, with the eventual goal to direct personalized cancer treatments …