COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection

WY Chi, YD Li, HC Huang, TEH Chan, SY Chow… - Journal of biomedical …, 2022 - Springer
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …

Effectiveness of COVID-19 vaccines against SARS-CoV-2 variants of concern: a systematic review and meta-analysis

B Zeng, L Gao, Q Zhou, K Yu, F Sun - BMC medicine, 2022 - Springer
Background It was urgent and necessary to synthesize the evidence for vaccine
effectiveness (VE) against SARS-CoV-2 variants of concern (VOC). We conducted a …

Community transmission and viral load kinetics of the SARS-CoV-2 delta (B. 1.617. 2) variant in vaccinated and unvaccinated individuals in the UK: a prospective …

A Singanayagam, S Hakki, J Dunning… - The lancet infectious …, 2022 - thelancet.com
Summary Background The SARS-CoV-2 delta (B. 1.617. 2) variant is highly transmissible
and spreading globally, including in populations with high vaccination rates. We aimed to …

Risk of infection, hospitalisation, and death up to 9 months after a second dose of COVID-19 vaccine: a retrospective, total population cohort study in Sweden

P Nordström, M Ballin, A Nordström - The Lancet, 2022 - thelancet.com
Background Vaccine effectiveness against COVID-19 beyond 6 months remains
incompletely understood. We aimed to investigate the effectiveness of COVID-19 …

Estimated effectiveness of COVID-19 vaccines against Omicron or Delta symptomatic infection and severe outcomes

SA Buchan, H Chung, KA Brown, PC Austin… - JAMA network …, 2022 - jamanetwork.com
Importance The incidence of SARS-CoV-2 infection, including among individuals who have
received 2 doses of COVID-19 vaccine, increased substantially following the emergence of …

Risk of SARS-CoV-2 reinfection and COVID-19 hospitalisation in individuals with natural and hybrid immunity: a retrospective, total population cohort study in Sweden

P Nordström, M Ballin, A Nordström - The Lancet Infectious Diseases, 2022 - thelancet.com
Background Real-world evidence supporting vaccination against COVID-19 in individuals
who have recovered from a previous SARS-CoV-2 infection is sparse. We aimed to …

Effectiveness of Covid-19 vaccines in ambulatory and inpatient care settings

MG Thompson, E Stenehjem, S Grannis… - … England Journal of …, 2021 - Mass Medical Soc
Background There are limited data on the effectiveness of the vaccines against symptomatic
coronavirus disease 2019 (Covid-19) currently authorized in the United States with respect …

Effectiveness of COVID-19 vaccines against symptomatic SARS-CoV-2 infection and severe outcomes with variants of concern in Ontario

S Nasreen, H Chung, S He, KA Brown, JB Gubbay… - Nature …, 2022 - nature.com
SARS-CoV-2 variants of concern (VOC) are more transmissible and may have the potential
for increased disease severity and decreased vaccine effectiveness. We estimated the …

Evaluation of the relative virulence of novel SARS-CoV-2 variants: a retrospective cohort study in Ontario, Canada

DN Fisman, AR Tuite - Cmaj, 2021 - Can Med Assoc
Background: Between February and June 2021, the initial wild-type strains of SARS-CoV-2
were supplanted in Ontario, Canada, by new variants of concern (VOCs), first those with the …

[HTML][HTML] Effect of Delta variant on viral burden and vaccine effectiveness against new SARS-CoV-2 infections in the UK

KB Pouwels, E Pritchard, PC Matthews, N Stoesser… - Nature medicine, 2021 - nature.com
The effectiveness of the BNT162b2 and ChAdOx1 vaccines against new severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infections requires continuous re …