Membranes under the magnetic lens: a dive into the diverse world of membrane protein structures using Cryo-EM

SJ Piper, RM Johnson, D Wootten, PM Sexton - Chemical reviews, 2022 - ACS Publications
Membrane proteins are highly diverse in both structure and function and can, therefore,
present different challenges for structure determination. They are biologically important for …

TonB-dependent transport across the bacterial outer membrane

A Silale, B van den Berg - Annual Review of Microbiology, 2023 - annualreviews.org
TonB-dependent transporters (TBDTs) are present in all gram-negative bacteria and
mediate energy-dependent uptake of molecules that are too scarce or large to be taken up …

Microenvironment-responsive metal-phenolic nanozyme release platform with antibacterial, ROS scavenging, and osteogenesis for periodontitis

Y Xu, Y Luo, Z Weng, H Xu, W Zhang, Q Li, H Liu… - ACS …, 2023 - ACS Publications
Periodontitis is a chronic inflammatory disease deriving from dental plaque, characterized by
the excessive accumulation of reactive oxygen species (ROS), matrix metalloproteinase …

Inflammation-associated nitrate facilitates ectopic colonization of oral bacterium Veillonella parvula in the intestine

DF Rojas-Tapias, EM Brown, ER Temple… - Nature …, 2022 - nature.com
Colonization of the intestine by oral microbes has been linked to multiple diseases such as
inflammatory bowel disease and colon cancer, yet mechanisms allowing expansion in this …

Identification and cultivation of anaerobic bacterial scavengers of dead cells

Y Hirakata, R Mei, K Morinaga, T Katayama… - The ISME …, 2023 - academic.oup.com
The cycle of life and death and Earth's carbon cycle (s) are intimately linked, yet how
bacterial cells, one of the largest pools of biomass on Earth, are recycled back into the …

Outer membrane utilisomes mediate glycan uptake in gut Bacteroidetes

JBR White, A Silale, M Feasey, T Heunis, Y Zhu… - Nature, 2023 - nature.com
Bacteroidetes are abundant members of the human microbiota, utilizing a myriad of diet-and
host-derived glycans in the distal gut. Glycan uptake across the bacterial outer membrane of …

Insights into SusCD-mediated glycan import by a prominent gut symbiont

DA Gray, JBR White, AO Oluwole, P Rath… - Nature …, 2021 - nature.com
In Bacteroidetes, one of the dominant phyla of the mammalian gut, active uptake of large
nutrients across the outer membrane is mediated by SusCD protein complexes via a “pedal …

TonB‐dependent transporters in the Bacteroidetes: unique domain structures and potential functions

RM Pollet, LM Martin, NM Koropatkin - Molecular Microbiology, 2021 - Wiley Online Library
The human gut microbiota endows the host with a wealth of metabolic functions central to
health, one of which is the degradation and fermentation of complex carbohydrates. The …

Investigation of the Genus Flavobacterium as a Reservoir for Fish-Pathogenic Bacterial Species: the Case of Flavobacterium collinsii

BH Lee, P Nicolas, IB Saticioglu, B Fradet… - Applied and …, 2023 - Am Soc Microbiol
Bacteria of the genus Flavobacterium are recovered from a large variety of environments.
Among the described species, Flavobacterium psychrophilum and Flavobacterium …

The ton motor

AC Ratliff, SK Buchanan, H Celia - Frontiers in Microbiology, 2022 - frontiersin.org
The Ton complex is a molecular motor at the inner membrane of Gram-negative bacteria that
uses a proton gradient to apply forces on outer membrane (OM) proteins to permit active …