[HTML][HTML] Laboratory diagnosis of Clostridium difficile disease

M Delmée - Clinical Microbiology and Infection, 2001 - Elsevier
The laboratory diagnosis of Clostridium difficile-associated disease (CDAD) is based on
culture and toxin detection in fecal specimens. Culture is performed on a commercially …

Clostridium difficile-associated diarrhea and colitis: Clinical manifestations, diagnosis, and treatment

RK Cleary - Diseases of the colon & rectum, 1998 - Springer
PURPOSE: This review examines the pathogenesis, clinical manifestations, diagnosis, and
current medical and operative strategies in the treatment of Clostridium difficile diarrhea and …

Clostridium difficile Testing in the Clinical Laboratory by Use of Multiple Testing Algorithms

SM Novak-Weekley, EM Marlowe… - Journal of clinical …, 2010 - Am Soc Microbiol
The incidence of Clostridium difficile infection (CDI) has risen almost 3-fold in the United
States over the past decade, emphasizing the need for rapid and accurate tests for CDI. The …

Rapid Detection of Clostridium difficile in Feces by Real-Time PCR

SD Bélanger, M Boissinot, N Clairoux… - Journal of clinical …, 2003 - Am Soc Microbiol
Clostridium difficile is the major causative agent of nosocomial antibiotic-associated
diarrhea, colitis, and pseudomembranous colitis. The pathogenicity of C. difficile is closely …

Diagnostic Accuracy of Real-time Polymerase Chain Reaction in Detection of Clostridium difficile in the Stool Samples of Patients With Suspected Clostridium difficile …

A Deshpande, V Pasupuleti… - Clinical Infectious …, 2011 - academic.oup.com
Background. Current detection methods for Clostridium difficile infection (CDI) can be time-
consuming and have variable sensitivities. Real-time polymerase chain reaction (PCR) may …

Epidemiology, diagnosis and treatment of Clostridium difficile infection

M Bassetti, G Villa, D Pecori, A Arzese… - Expert review of anti …, 2012 - Taylor & Francis
Clostridium difficile infection (CDI) is considered to be the main cause of bacterial infectious
diarrhea in nosocomial settings. Since the beginning of the new century a continuous rise in …

The diagnosis of Clostridium difficile-associated disease.

JS Brazier - The Journal of antimicrobial chemotherapy, 1998 - academic.oup.com
There are well-documented risk factors associated with the development of antibiotic-
associated diarrhoea; knowledge of these and of the typical signs and symptoms should …

Molecular techniques for diagnosis of Clostridium difficile infection: systematic review and meta-analysis

JC O'Horo, A Jones, M Sternke, C Harper… - Mayo Clinic …, 2012 - Elsevier
Objective To assess the usefulness of 2 rapid molecular diagnostic techniques, polymerase
chain reaction (PCR) and loop-mediated isothermal amplification (LAMP), in Clostridium …

Clostridium difficile infections in animals with special reference to the horse. A review

V Båverud - Veterinary quarterly, 2002 - Taylor & Francis
In human medicine, Clostridium (C.) difficile is since many years a well‐known cause of
nosocomial diarrhea induced by antibiotic treatment. In horses, C. difficile was recently …

Detection of enterotoxigenic Bacteroides fragilis by PCR

A Pantosti, M Malpeli, M Wilks… - Journal of clinical …, 1997 - Am Soc Microbiol
Strains of enterotoxigenic Bacteroides fragilis (ETBF) are associated with diarrhea in young
farm animals and, at least in particular settings, in children. Enterotoxin production by ETBF …