Almost all currently available treatments for inflammatory bowel disease (IBD) act by
inhibiting inflammation, often blocking specific inflammatory molecules. However, given the …

The gastrointestinal tract consists of an enormous surface area that is optimized to efficiently
absorb nutrients, water, and electrolytes from food. At the same time, it needs to provide a …

11.1. General The treatment strategy for ulcerative colitis [UC] is mainly based on the
severity, distribution [proctitis, left-sided, extensive] 1 and pattern of disease. The latter …

When deciding the appropriate treatment strategy for active ulcerative colitis one should
consider the activity, distribution (proctitis, left-sided, extensive 1), and pattern of disease …

The gut mucosa is constantly challenged by a bombardment of foreign antigens and
environmental microorganisms. As such, the precise regulation of the intestinal barrier …

BACKGROUND: Asthma is a complex disease involving gene and environment interactions.
Although atopy is a strong predisposing risk factor for asthma, local tissue susceptibilities …

Crohn's disease and ulcerative colitis are two idiopathic inflammatory bowel disorders. In
this paper we discuss the current diagnostic approach, their pathology, natural course, and …

Two broad hypotheses have arisen regarding the fundamental nature of the pathogenesis of
inflammatory bowel diseases (IBDs, which include ulcerative colitis and Crohn disease). The …

Ulcerative colitis (UC) is a common gastrointestinal disorder in adults. Recent advances in
pathophysiology, immunology, and pharmaceutical science have resulted in a large number …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …