Tetrodotoxin: Chemistry, toxicity, source, distribution and detection
Tetrodotoxin (TTX) is a naturally occurring toxin that has been responsible for human
intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated …
intoxications and fatalities. Its usual route of toxicity is via the ingestion of contaminated …
Tetrodotoxin, an extremely potent marine neurotoxin: Distribution, toxicity, origin and therapeutical uses
J Lago, LP Rodríguez, L Blanco, JM Vieites… - Marine drugs, 2015 - mdpi.com
Tetrodotoxin (TTX) is a potent neurotoxin responsible for many human intoxications and
fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be …
fatalities each year. The origin of TTX is unknown, but in the pufferfish, it seems to be …
Tetrodotoxin-producing bacteria: Detection, distribution and migration of the toxin in aquatic systems
TY Magarlamov, DI Melnikova, AV Chernyshev - Toxins, 2017 - mdpi.com
This review is devoted to the marine bacterial producers of tetrodotoxin (TTX), a potent non-
protein neuroparalytic toxin. In addition to the issues of the ecology and distribution of TTX …
protein neuroparalytic toxin. In addition to the issues of the ecology and distribution of TTX …
On the origins and biosynthesis of tetrodotoxin
The potent neurotoxin tetrodotoxin (TTX) has been identified from taxonomically diverse
marine organisms. TTX possesses a unique cage-like structure, however, its biosynthesis …
marine organisms. TTX possesses a unique cage-like structure, however, its biosynthesis …
Distribution and origin of tetrodotoxin
K Miyazawa, T Noguchi - Journal of Toxicology: Toxin Reviews, 2001 - Taylor & Francis
Among the marine toxins relevant for human intoxication, tetrodo-toxin (TTX) has been
known as one of the most prejudicial. Puffer fish were originally thought to be the only …
known as one of the most prejudicial. Puffer fish were originally thought to be the only …
Tetrodotoxin poisoning
DF Hwang, T Noguchi - Advances in Food and Nutrition Research, 2007 - Elsevier
Tetrodotoxin (TTX) is one of the most potent and oldest known neurotoxins. The poisoning
cases due to ingestion of TTX‐containing marine animals, especially for puffer, have …
cases due to ingestion of TTX‐containing marine animals, especially for puffer, have …
The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts
Rough-skinned newts (Taricha granulosa) use tetrodotoxin (TTX) to block voltage-gated
sodium (Nav) channels as a chemical defense against predation. Interestingly, newts exhibit …
sodium (Nav) channels as a chemical defense against predation. Interestingly, newts exhibit …
Pharmacology of tetrodotoxin
T Narahashi - Journal of Toxicology: Toxin Reviews, 2001 - Taylor & Francis
Tetrodotoxin (TTX) is a potent neurotoxin originally found in the ovary and liver of puffer fish.
It has now become abundantly clear that TTX is not synthesized in the puffer fish, and that it …
It has now become abundantly clear that TTX is not synthesized in the puffer fish, and that it …
An overview on the origin and production of tetrodotoxin, a potent neurotoxin
Tetrodotoxin (TTX) is a deadly neurotoxin which selectively inhibits Na+ activation
mechanism of nerve impulse, without affecting the permeability of K+ ions. Because of this …
mechanism of nerve impulse, without affecting the permeability of K+ ions. Because of this …
The association of bacterial C9-based TTX-like compounds with Prorocentrum minimum opens new uncertainties about shellfish seafood safety
I Rodríguez, A Alfonso, E Alonso, JA Rubiolo, M Roel… - Scientific reports, 2017 - nature.com
Abstract In 2012, Tetrodotoxin (TTX) was identified in mussels and linked to the presence of
Prorocentrum minimum (P. minimum) in Greece. The connexion between TTX and P …
Prorocentrum minimum (P. minimum) in Greece. The connexion between TTX and P …