Introduction There is a continuing worldwide shortage of organs from deceased human
donors for transplantation into patients with end-stage organ failure. Genetically engineered …

At the 2015 combined congress of the Cell Transplant Society, International Pancreas and
Islet Transplant Association, and International Xenotransplantation Association, a …

摘要β 细胞补充治疗, 包括同种异体胰腺与胰岛移植, 对于脆性1 型糖尿病患者来说可使其
HbA1c 水平正常化, 但是供体短缺是个严重的问题. 为了克服这个问题, 异种移植是一种吸引人 …

This review will detail the current status of islet xenotransplantation as a potential treatment
for type I diabetes mellitus, focusing on recent advances in porcine xenogeneic islet …

Background Islet transplantation is an effective therapy for selected patients with type 1
diabetes with labile glycemic control and hypoglycemic unawareness, but donor organs are …

Islet allotransplantation results in increasing success in treating type 1 diabetes, but the
shortage of deceased human donor pancreata limits progress. Islet xenotransplantation …

Tolerogenic dendritic cells and T-regulatory cells are two immune cell populations with the
potential to prevent the onset of clinical stage type 1 diabetes, and manage the beginning of …

The continual critical shortage of organs and cells from deceased human donors has
stimulated research in the field of cross-species transplantation (xenotransplantation), with …

Porcine islet xenotransplantation represents a promising therapy for severe diabetes
mellitus. Long-term culture of porcine islets is a crucial challenge to permit the on-demand …

Allogeneic islet transplantation into the liver in combination with immune suppressive drug
therapy is widely regarded as a potential cure for type 1 diabetes. However, the intrahepatic …