Preeclampsia is a serious complication of pregnancy where it affects 5–8% of all
pregnancies. It increases the morbidity and mortality of both the fetus and pregnant woman …

Diabetes is one of the leading causes of kidney disease. Diabetic kidney disease (DKD) is a
major cause of end-stage kidney disease (ESKD) worldwide, and it is linked to an increase …

OBJECTIVE Diabetic kidney disease (DKD) is the single leading cause of kidney failure in
the US, for which a cure has not yet been found. The aim of our study was to provide an …

Pericytes are a heterogeneous population of cells located in the blood vessel wall. They
were first identified in the 19th century by Rouget, however their biological role and potential …

Abstract Between 20% and 40% of patients with diabetes ultimately develop diabetic
nephropathy, which in the US is the most common cause of end-stage renal disease …

Podocyte detachment and reduced endothelial cell fenestration and relationships between
these features and the classic structural changes of diabetic nephropathy have not been …

Proteinuria is the hallmark of diabetic kidney disease (DKD) and is an independent risk
factor for both renal disease progression, and cardiovascular disease. Although the …

Diabetes mellitus contributes greatly to morbidity, mortality, and overall health care costs. In
major part, these outcomes derive from the high incidence of progressive kidney dysfunction …

Diabetes mellitus is characterized by a lack of insulin causing elevated blood glucose, often
with associated insulin resistance. Over time, especially in genetically susceptible …

Progressive renal diseases are associated with rarefaction of peritubular capillaries, but the
ultrastructural and functional alterations of the microvasculature are not well described. To …