The contributions of soil microbial diversity for the multifunctionality of ecosystem functions
remain little understood despite the well-known importance of soil microbial communities for …

The discovery of drivers of cancer has traditionally focused on protein-coding genes,,–. Here
we present analyses of driver point mutations and structural variants in non-coding regions …

Computational methods have made substantial progress in improving the accuracy and
throughput of pathology workflows for diagnostic, prognostic, and genomic prediction. Still …

Malignant transformation can result in melanoma cells that resemble different stages of their
embryonic development. Our gene expression analysis of human melanoma cell lines and …

Background and Aims Manual histological assessment is currently the accepted standard for
diagnosing and monitoring disease progression in NASH, but is limited by variability in …

Nitrogen is an essential macronutrient for plant growth and basic metabolic processes. The
application of nitrogen-containing fertilizer increases yield, which has been a substantial …

Microbial interactions shape the structure and function of microbial communities; microbial
co-occurrence networks in specific environments have been widely developed to explore …

Quantitative mass spectrometry has established proteome-wide regulation of protein
abundance and post-translational modifications in various biological processes. Here, we …

Monitoring drug–target interactions with methods such as the cellular thermal-shift assay
(CETSA) is well established for simple cell systems but remains challenging in vivo. Here we …

Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer, but a
comprehensive description of its genomic landscape is lacking. We report the whole …