History, discovery, and classification of lncRNAs
J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
The Landscape of long noncoding RNA classification
GS Laurent, C Wahlestedt, P Kapranov - Trends in genetics, 2015 - cell.com
Advances in the depth and quality of transcriptome sequencing have revealed many new
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
classes of long noncoding RNAs (lncRNAs). lncRNA classification has mushroomed to …
Targeting long non-coding RNA to therapeutically upregulate gene expression
C Wahlestedt - Nature reviews Drug discovery, 2013 - nature.com
The majority of currently available drugs and tool compounds exhibit an inhibitory
mechanism of action and there is a relative lack of pharmaceutical agents that are capable …
mechanism of action and there is a relative lack of pharmaceutical agents that are capable …
Specific expression of long noncoding RNAs in the mouse brain
A major proportion of the mammalian transcriptome comprises long RNAs that have little or
no protein-coding capacity (ncRNAs). Only a handful of such transcripts have been …
no protein-coding capacity (ncRNAs). Only a handful of such transcripts have been …
Roles of long noncoding RNAs in brain development, functional diversification and neurodegenerative diseases
P Wu, X Zuo, H Deng, X Liu, L Liu, A Ji - Brain research bulletin, 2013 - Elsevier
Long noncoding RNAs (lncRNAs) have been attracting immense research interest, while
only a handful of lncRNAs have been characterized thoroughly. Their involvement in the …
only a handful of lncRNAs have been characterized thoroughly. Their involvement in the …
lncRNAdb: a reference database for long noncoding RNAs
Large numbers of long RNAs with little or no protein-coding potential [long noncoding RNAs
(lncRNAs)] are being identified in eukaryotes. In parallel, increasing data describing the …
(lncRNAs)] are being identified in eukaryotes. In parallel, increasing data describing the …
Cis-acting noncoding RNAs: friends and foes
S Guil, M Esteller - Nature structural & molecular biology, 2012 - nature.com
In recent years, the number and types of known functional noncoding RNAs have increased
considerably. A subset of both short-and long-sized species are known to be involved in the …
considerably. A subset of both short-and long-sized species are known to be involved in the …
Long noncoding RNAs in mouse embryonic stem cell pluripotency and differentiation
The transcriptional networks that regulate embryonic stem (ES) cell pluripotency and lineage
specification are the subject of considerable attention. To date such studies have focused …
specification are the subject of considerable attention. To date such studies have focused …
The reality of pervasive transcription
The Reality of Pervasive Transcription | PLOS Biology Skip to main content Advertisement
PLOS Biology Browse Current Issue Journal Archive Collections Find and Read Articles Publish …
PLOS Biology Browse Current Issue Journal Archive Collections Find and Read Articles Publish …
The expanding RNA polymerase III transcriptome
The role of RNA polymerase (Pol) III in eukaryotic transcription is commonly thought of as
being restricted to a small set of highly expressed, housekeeping non–protein-coding (nc) …
being restricted to a small set of highly expressed, housekeeping non–protein-coding (nc) …