Introduction Paracetamol is one of the most used medicines worldwide and is the most
common important poisoning in high-income countries. In overdose, paracetamol causes …

Drug-induced liver injury (DILI), herbal-induced liver injury, and herbal and dietary
supplement (HDS)-induced liver injury are an important aspect of drug safety. Knowledge …

Introduction Acetaminophen (paracetamol) is a commonly used analgesic and antipyretic
agent, which is safe in therapeutic doses. Acetaminophen poisoning due to self-harm or …

Fomepizole should be used more liberally in paracetamol overdose - Filip - 2023 - British Journal of
Clinical Pharmacology - Wiley Online Library Skip to Article Content Skip to Article Information …

Background and Objectives: Over-the-counter availability and a good safety profile make
paracetamol one of the most common analgesics in developed countries but also the …

Background Risk stratification in paracetamol (acetaminophen) poisoning is crucial because
hepatotoxicity is common and can be mitigated with treatment. However, current risk …

Historically, intravenous acetylcysteine has been delivered at a fixed dose and duration of
300 mg/kg over 20 to 21 hours to nearly every patient deemed to be at any risk for …

Introduction: Although the hepatotoxicity of acetaminophen is a well-known problem, the
search for reliable biomarker of toxicity is still a current issue as clinical tools are missing to …

—Acetaminophen poisoning is among the most common causes of medication-related
poisoning and death. Acetaminophen poisoning may occur following a single acute …

Objectives: There have been few studies of pharmacobezoar formation, but they can be an
important contributor to overdose toxicity. Pharmacobezoars may explain the delayed peak …