Mesenchymal stem cells therapy in companion animals: useful for immune-mediated diseases?

IE Dias, PO Pinto, LC Barros, CA Viegas, IR Dias… - BMC veterinary …, 2019 - Springer
Mesenchymal stem cells are multipotent cells, with capacity for self-renewal and
differentiation into tissues of mesodermal origin. These cells are possible therapeutic agents …

Mesenchymal stem cell–based therapy as a new approach for the treatment of systemic sclerosis

X Zhuang, X Hu, S Zhang, X Li, X Yuan… - Clinical reviews in allergy & …, 2022 - Springer
Systemic sclerosis (SSc) is an intractable autoimmune disease with unmet medical needs.
Conventional immunosuppressive therapies have modest efficacy and obvious side effects …

Therapeutic mesenchymal stromal stem cells: Isolation, characterization and role in equine regenerative medicine and metabolic disorders

M Al Naem, L Bourebaba, K Kucharczyk… - Stem cell reviews and …, 2020 - Springer
Mesenchymal stromal cells (MSC) have become a popular treatment modality in equine
orthopaedics. Regenerative therapies are especially interesting for pathologies like …

Translational animal models provide insight into mesenchymal stromal cell (MSC) secretome therapy

RM Harman, C Marx, GR Van de Walle - Frontiers in Cell and …, 2021 - frontiersin.org
The therapeutic potential of the mesenchymal stromal cell (MSC) secretome, consisting of all
molecules secreted by MSCs, is intensively studied. MSCs can be readily isolated …

Mesenchymal stem cell basic research and applications in dog medicine

MB Gugjoo, A Amarpal… - Journal of cellular …, 2019 - Wiley Online Library
The stem cells, owing to their special characteristics like self‐renewal, multiplication,
homing, immunomodulation, anti‐inflammatory, and dedifferentiation are considered to carry …

GMP-compliant production of human placenta-derived mesenchymal stem cells

HR Aghayan, M Payab, F Mohamadi-Jahani… - Stem cells and good …, 2021 - Springer
Mesenchymal stem cells are one of the most attractive sources for stem cell research and
therapy. Their safety and efficacy have been demonstrated in many clinical trials. Because of …

Dog Mesenchymal Stem Cell Basic Research and Potential Applications

MB Gugjoo, A Pal, GT Sharma - Mesenchymal Stem Cell in Veterinary …, 2020 - Springer
Mesenchymal stem cells (MSCs) being available in numerous adult tissues and foetal
membranes have been harvested from almost all these sources in dog. Due to the presence …

The role of mesenchymal stem cell transplantation for ischemic stroke and recent research developments

L Zhou, J Wang, J Huang, X Song, Y Wu… - Frontiers in …, 2022 - frontiersin.org
Ischemic stroke is a common cerebrovascular disease that seriously affects human health.
However, most patients do not practice self-care and cannot rely on the current clinical …

Mesenchymal stem cells: generalities and clinical significance in feline and canine medicine

M Baouche, M Ochota, Y Locatelli, P Mermillod… - Animals, 2023 - mdpi.com
Simple Summary Veterinary regenerative medicine is an area of active research in which
mesenchymal stem cells are applied. Mesenchymal stem cells (MSCs) are cells that can be …

Phenotypical characterization and neurogenic differentiation of rabbit adipose tissue-derived mesenchymal stem cells

M Tirpáková, J Vašíček, A Svoradová, A Baláži… - Genes, 2021 - mdpi.com
Although the rabbit is a frequently used biological model, the phenotype of rabbit adipose-
derived mesenchymal stem cells (rAT-MSCs) is not well characterized. One of the reasons is …