Abstract Cancers of Unknown Primary (CUP) comprise a heterogeneous clinical entity of
confirmed metastatic cancer where the primary site of origin is undetectable. It has a poor …

Cancer of unknown primary (CUP) is a rare malignancy that presents with metastatic
disease and no identifiable site of origin. Most patients have unfavorable features and …

Background Cancer of unknown primary (CUP) accounts for approximately 3% of all
malignancies. Avoiding immune destruction is a major cancer characteristic and therapies …

Abstract Cancers of Unknown Primary Site (CUP) account for approximately 1–3% of all
malignant neoplasms. It represents a heterogeneous group of malignancies without a …

The concept of Cancer of Unknown Primary (CUP) has evolved with the advent of medical
oncology. CUP can be difficult to diagnose and represents 2 to 5% of new cancers, therefore …

Simple Summary Patients with cancer of unknown primary site suffer the burden of an
uncertain disease, which is characterized by the impossibility to identify the tissue where the …

Cancer of unknown primary (CUP) is an umbrella term used to classify a heterogeneous
group of metastatic cancers based on the absence of an identifiable primary tumor …

Background Cancer of unknown primary (CUP) accounts for approximately 3% of all
malignancies. Despite extensive laboratory and imaging efforts, the primary site usually …

Background In∼ 3%-5% of patients with metastatic disease, tumor origin remains unknown
despite modern imaging techniques and extensive pathology work-up. With long diagnostic …

Carcinoma of unknown primary site (CUP) is diagnosed in approximately 3% of patients with
advanced cancer, and most patients have traditionally been treated with empiric …