Measles encephalitis: towards new therapeutics

M Ferren, B Horvat, C Mathieu - Viruses, 2019 - mdpi.com
Measles remains a major cause of morbidity and mortality worldwide among vaccine
preventable diseases. Recent decline in vaccination coverage resulted in re-emergence of …

Host–Pathogen interactions influencing zoonotic spillover potential and transmission in humans

B Escudero-Pérez, A Lalande, C Mathieu, P Lawrence - Viruses, 2023 - mdpi.com
Emerging infectious diseases of zoonotic origin are an ever-increasing public health risk
and economic burden. The factors that determine if and when an animal virus is able to spill …

Hamster organotypic modeling of SARS-CoV-2 lung and brainstem infection

M Ferren, V Favède, D Decimo, M Iampietro… - Nature …, 2021 - nature.com
SARS-CoV-2 has caused a global pandemic of COVID-19 since its emergence in December
2019. The infection causes a severe acute respiratory syndrome and may also spread to …

Inhibition of Coronavirus Entry In Vitro and Ex Vivo by a Lipid-Conjugated Peptide Derived from the SARS-CoV-2 Spike Glycoprotein HRC Domain

VK Outlaw, FT Bovier, MC Mears, MN Cajimat, Y Zhu… - MBio, 2020 - Am Soc Microbiol
The emergence of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the
etiological agent of the 2019 coronavirus disease (COVID-19), has erupted into a global …

Molecular features of the measles virus viral fusion complex that favor infection and spread in the brain

C Mathieu, FT Bovier, M Ferren, NAP Lieberman… - MBio, 2021 - Am Soc Microbiol
Measles virus (MeV) bearing a single amino acid change in the fusion protein (F)—L454W—
was isolated from two patients who died of MeV central nervous system (CNS) infection. This …

Measles pathogenesis, immune suppression and animal models

BM Laksono, RD de Vries, WP Duprex… - Current Opinion in …, 2020 - Elsevier
Highlights•Measles virus utilises different cellular receptors to infect multiple cell
types.•Measles paradoxically induces lifelong immunity and transient immune …

Multiple receptors involved in invasion and neuropathogenicity of canine distemper virus: a review

J Zhao, Y Ren - Viruses, 2022 - mdpi.com
The canine distemper virus (CDV) is a morbillivirus that infects a broad range of terrestrial
carnivores, predominantly canines, and is associated with high mortality. Similar to another …

[HTML][HTML] Antiviral activity of nitazoxanide against Morbillivirus infections

D Stelitano, S La Frazia, A Ambrosino… - Journal of Virus …, 2023 - Elsevier
The measles virus (MeV) and canine distemper virus (CDV) belong to the genus
Morbillivirus of the Paramyxoviridae family. They are enveloped viruses harboring a non …

Measles resurgence and drug development

RK Plemper - Current opinion in virology, 2020 - Elsevier
Measles caused an estimated minimum of one million fatalities annually before vaccination.
Outstanding progress towards controlling the virus has been made since the measles …

Mechanisms of viral persistence in the brain and therapeutic approaches

A Nath, TP Johnson - The FEBS Journal, 2022 - Wiley Online Library
There is growing recognition of the diversity of viruses that can infect the cells of the central
nervous system (CNS). While the majority of CNS infections are successfully cleared by the …