Chronic inflammatory lesions of the placenta are characterized by the infiltration of the organ
by lymphocytes, plasma cells, and/or macrophages and may result from infections (viral …

CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

Chemokines, binding their various G protein-coupled receptors, lead the way for leukocytes
in health and inflammation. Yet chemokine receptor expression is not limited to leukocytes …

Abstract IFN-γ-inducible protein 10 (IP-10, CXCL10), a chemokine secreted from cells
stimulated with type I and II IFNs and LPS, is a chemoattractant for activated T cells …

Understanding SARS-CoV-2 associated immune pathology is crucial to develop pan-
effective vaccines and treatments. Here we investigate the immune events from the acute …

Cytokines may be crucially involved in the pathogenesis of inflammatory bowel diseases
(IBD), but it remains controversial whether interferon (IFN)-γ, a typical proinflammatory …

Preeclampsia (PE) is a complex, hypertensive disorder of pregnancy, demonstrating
considerable variability in maternal symptoms and fetal outcomes. Unfortunately, prior …

Organ transplantation appears today to be the best alternative to replace the loss of vital
organs induced by various diseases. Transplants can, however, also be rejected by the …

Chemokines are a group of peptides of low molecular weight that induce the chemotaxis of
different leukocyte subtypes. The major function of chemokines is the recruitment of …