The management of colorectal liver metastases amenable of surgical resection: How to shape treatment strategies according to clinical, radiological, pathological and …
MM Germani, B Borelli, P Boraschi, C Antoniotti… - Cancer Treatment …, 2022 - Elsevier
Metastatic colorectal cancer (mCRC) patients have poor chances of long term survival,
being< 15% of them still alive after 5 years from diagnosis. Nonetheless, patients with …
being< 15% of them still alive after 5 years from diagnosis. Nonetheless, patients with …
KRAS mutations are influential in driving hepatic metastases and predicting outcome in colorectal cancer
Metastatic colorectal cancer (CRC) is a topic of intense research. KRAS mutations have
emerged as aggressive drivers of disease. Here we discuss the role of KRAS mutations in …
emerged as aggressive drivers of disease. Here we discuss the role of KRAS mutations in …
The optimal cut‐off values for tumor size, number of lesions, and CEA levels in patients with surgically treated colorectal cancer liver metastases: An international …
Abstract Background and Objectives Despite the long‐standing consensus on the
importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as …
importance of tumor size, tumor number and carcinoembryonic antigen (CEA) levels as …
Early evaluation of liver metastasis using spectral CT to predict outcome in patients with colorectal cancer treated with FOLFOXIRI and bevacizumab
S Li, L Yuan, M Yue, Y Xu, S Liu, F Wang, X Liu… - Cancer Imaging, 2023 - Springer
Purpose Early evaluation of the efficacy of first-line chemotherapy combined with
bevacizumab in patients with colorectal cancer liver metastasis (CRLM) remains …
bevacizumab in patients with colorectal cancer liver metastasis (CRLM) remains …
Mutant KRAS as a prognostic biomarker after hepatectomy for rectal cancer metastases: Does the primary disease site matter?
Background The prognostic implication of mutant KRAS (mKRAS) among patients with
primary disease in the rectum remains unknown. Methods From 2000 to 2018, patients …
primary disease in the rectum remains unknown. Methods From 2000 to 2018, patients …
RAS mutation associated with short surgically controllable period in colorectal liver metastases: a retrospective study
S Ito, T Takamoto, S Nara, D Ban, T Mizui… - World Journal of …, 2024 - Springer
Background The prognostic implications of the RAS status in colorectal cancer liver
metastasis (CRLM) remain unclear. This study investigated the prognostic significance of …
metastasis (CRLM) remain unclear. This study investigated the prognostic significance of …
[HTML][HTML] Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases
D Xu, YY Wang, XL Yan, J Li, K Wang… - Journal of …, 2021 - ncbi.nlm.nih.gov
Background Preoperative chemotherapy has widely been used in colorectal cancer liver
metastasis (CRLM). Pathological response to chemotherapy is very important in evaluating …
metastasis (CRLM). Pathological response to chemotherapy is very important in evaluating …
Differential effects of KRAS mutational status on long-term survival according to the timing of colorectal liver metastases
N Sakai, K Furukawa, T Takayashiki, S Kuboki… - BMC cancer, 2021 - Springer
Background The relationship between KRAS mutational status and timing of colorectal liver
metastasis (CRLM) remains unclear. This study evaluated the relationship between KRAS …
metastasis (CRLM) remains unclear. This study evaluated the relationship between KRAS …
Colorectal Cancer Liver Metastasis—State-of-the-Art and Future Perspectives
A Ruivo, RC Oliveira, P Silva-Vaz… - Gastrointestinal Disorders, 2023 - mdpi.com
The current management of colorectal cancer liver metastasis (CRCLM) patients involves a
multidisciplinary approach, with surgical resection remaining the primary curative option …
multidisciplinary approach, with surgical resection remaining the primary curative option …
CT-radiomics and pathological tumor response to systemic therapy: A predictive analysis for colorectal liver metastases. Development and internal validation of a …
Introduction The standard treatment of colorectal liver metastases (CRLM) is surgery with
perioperative chemotherapy. A tumor response to systemic therapy confirmed at pathology …
perioperative chemotherapy. A tumor response to systemic therapy confirmed at pathology …