Flaviviruses are vector-borne RNA viruses that can emerge unexpectedly in human
populations and cause a spectrum of potentially severe diseases including hepatitis …

Zika virus (ZIKV) is a mosquito-transmitted flavivirus that has emerged as a global health
threat because of its potential to generate explosive epidemics and ability to cause …

Zika virus (ZIKV), a mosquito-borne positive-stranded RNA virus of the family Flaviviridae
(genus Flavivirus), is now causing an unprecedented large-scale outbreak in the Americas …

Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Zika virus was discovered∼ 70 years ago in Uganda and maintained a low profile as a
human disease agent in Africa and Asia. Only recently has it caused explosive outbreaks in …

A major concern associated with ZIKV infection is the increased incidence of microcephaly
with frequent calcifications in infants born from infected mothers. To date, postmortem …

As placental mammals, the pregnant women and the fetus have intense and prolonged
interactions during gestation. There is increasing evidence that multiple molecular as well as …

Human cytomegalovirus (HCMV) is the most common viral infection acquired by the
developing human fetus and can result in damage to the developing central nervous system …

Extracellular vesicles (EVs) subtype, exosome is an extracellular nano-vesicle that sheds
from cells' surface and originates as intraluminal vesicles during endocytosis. Firstly, it was …

A recent outbreak of Zika virus in Brazil has led to a simultaneous increase in reports of
neonatal microcephaly. Zika targets cerebral neural precursors, a cell population essential …