Dopamine, immunity, and disease

B Channer, SM Matt, EA Nickoloff-Bybel, V Pappa… - Pharmacological …, 2023 - ASPET
The neurotransmitter dopamine is a key factor in central nervous system (CNS) function,
regulating many processes including reward, movement, and cognition. Dopamine also …

Where is dopamine and how do immune cells see it?: dopamine-mediated immune cell function in health and disease

SM Matt, PJ Gaskill - Journal of Neuroimmune Pharmacology, 2020 - Springer
Dopamine is well recognized as a neurotransmitter in the brain, and regulates critical
functions in a variety of peripheral systems. Growing research has also shown that …

Nucleus accumbens cytoarchitecture predicts weight gain in children

KM Rapuano, JS Laurent… - Proceedings of the …, 2020 - National Acad Sciences
The prevalence of obesity in children and adolescents worldwide has quadrupled since
1975 and is a key predictor of obesity later in life. Previous work has consistently observed …

[HTML][HTML] Dopamine, a co-regulatory component, bridges the central nervous system and the immune system

M Li, L Zhou, X Sun, Y Yang, C Zhang, T Wang… - Biomedicine & …, 2022 - Elsevier
Dopamine (DA) is a crucial neurotransmitter that plays an important role in maintaining
physiological function in human body. In the past, most studies focused on the relationship …

Anti-Inflammatory Effects of Peripheral Dopamine

SC Moore, PAS Vaz de Castro, D Yaqub… - International Journal of …, 2023 - mdpi.com
Dopamine is synthesized in the nervous system where it acts as a neurotransmitter.
Dopamine is also synthesized in a number of peripheral organs as well as in several types …

[HTML][HTML] Hypothalamic expression of huntingtin causes distinct metabolic changes in Huntington's disease mice

E Dickson, R Soylu-Kucharz, Å Petersén… - Molecular Metabolism, 2022 - Elsevier
Abstract Objective In Huntington's disease (HD), the disease-causing huntingtin (HTT)
protein is ubiquitously expressed and causes both central and peripheral pathology. In …

Dopaminergic pathways in obesity-associated inflammation

F Leite, L Ribeiro - Journal of Neuroimmune Pharmacology, 2020 - Springer
The overwhelming prevalence of obesity is a priority for public health compromising human
lifespan and representing important economic burden worldwide. Obesity is characterized …

Subcutaneous adipose tissue dopamine D2 receptor is increased in prediabetes and T2D

M Vranic, F Ahmed, R Kristófi, S Hetty, D Mokhtari… - Endocrine, 2024 - Springer
Purpose To evaluate the dopaminergic signaling in human adipose tissue in the context of
obesity and type 2 diabetes (T2D) and potential direct implications in adipose tissue …

Correlation between the dopaminergic system and inflammation disease: a review

P Ma, Y Ou - Molecular Biology Reports, 2023 - Springer
The dopaminergic system is inextricably linked with neurological diseases and addiction. In
recent years, many studies have found that the dopaminergic system involves in …

Lost in translation? On the need for convergence in animal and human studies on the role of dopamine in diet-induced obesity

LK Janssen, N Herzog, M Waltmann, N Breuer… - Current addiction …, 2019 - Springer
Abstract Purpose of Review Animal and human studies suggest that diet-induced obesity
and plasticity in the central dopaminergic system are linked. However, it is unclear whether …