Over the past several years, there has been a surge in blood biomarker studies examining
the value of plasma or serum neurofilament light (NfL) as a biomarker of neurodegeneration …

Alzheimer's and related diseases are significant health issues of this era. The
interdisciplinary use of deep learning in this field has shown great promise and gathered …

Numerous studies have investigated the impacts of common types of chronic pain (CP) on
patients' cognitive function and observed that CP was associated with later dementia. More …

Aging is associated with deterioration in dentate gyrus (DG) and CA3, both crucial
hippocampal subfields for age susceptible memory processes such as mnemonic …

Background: Neuroimaging bears the promise of providing new biomarkers that could refine
the diagnosis of dementia. Still, obtaining the pathology data required to validate the …

Background The hippocampus, with its complex subfields, is linked to numerous
neuropsychiatric traits. While most research has focused on its global structure or a few …

The microstructural characteristics of white and gray matter in mild cognitive impairment
(MCI) and the early-stage of Alzheimer's disease (AD) remain unclear. This study aimed to …

The hippocampal–entorhinal system supports cognitive function and is selectively
vulnerable to Alzheimer's disease (AD). Little is known about global transcriptomic changes …

Hippocampal subfields (HCsf) are brain regions important for memory function that are
vulnerable to decline with amnestic mild cognitive impairment (aMCI), which is often a …

Background DNA methylation is associated with cardiovascular (CV) disease. However, in
type 2 diabetes (T2D) patients, the role of gene methylation in the development of CV …