Experimental work during the past 15 years has demonstrated that endothelial cells in the
heart play an obligatory role in regulating and maintaining cardiac function, in particular, at …

Myocardial infarction is the major cause of death in the world. Over the last two decades,
coronary reperfusion therapy has become established for the management of acute …

Complex paracrine interactions exist between endothelial cells and cardiac myocytes in the
heart. Cardiac endothelial cells release (or metabolize) several diffusible agents (eg, nitric …

In this study we evaluate the effects of angiotensin-(1-7) on reperfusion arrhythmias in
isolated rat hearts. Rat hearts were perfused according to Langendorff technique and …

Myocardial ischemia and reperfusion (MI/R) initiates a cascade of polymorphonuclear
neutrophil (PMN)-mediated injury, the magnitude of which may be influenced by the …

Cytokine-induced NO production depresses myocardial contractility and has been shown to
be cytotoxic to cardiac myocytes. However, the mechanisms of cytokine-induced cardiac …

Altered Ca2+ homeostasis is a salient feature of heart disease, where the calcium release
channel ryanodine receptor (RyR) plays a major role. Accumulating data support the notion …

In the present study, the contribution of nitric oxide (NO), superoxide, and peroxynitrite to the
inflammatory response induced by myocardial ischemia-reperfusion (MI/R) was …

nitrates and other nitrovasodilators as the pharmacological- and myocardial effects of NO,
which have already been ly active principle of these drugs and has a therapeutic extensively …

We reviewed stable gastric pentadecapeptide BPC 157-NO-system-relation, its close
participation in Moncada's (maintained vascular integrity, platelets control) homeostatic …