Cocaine is a powerful stimulant of the sympathetic nervous system by inhibiting
catecholamine reuptake, stimulating central sympathetic outflow, and increasing the …

Renal disease in cocaine and heroin users is associated with the nephrotic syndrome, acute
glomerulonephritis, amyloidosis, interstitial nephritis, and rhabdomyolysis. The …

Drug use is seen more as an individualistic behaviour and is therefore not readily conceived
of from a population perspective. There is general recognition of several phases and …

Substance abuse has been increasing steadily in the UK and some other countries. Recent
evidence suggests more than 40% of young people have tried illicit drugs at some time …

Milroy CM & Parai JL (2011) Histopathology 59, 579–593 The histopathology of drugs of
abuse The use of drugs for recreational purposes is widespread. The drugs used can be …

Cocaine use in the United States continues to be a significant problem. Cocaine use is
responsible for approximately 143,000 Emergency Department visits annually. The cardiac …

Cocaine produces a pattern of cardiovascular responses that are associated with apparent
myocardial ischemia, arrhythmias, and other life-threatening complications in some …

Cocaine abuse has reached epidemic proportions in the United States, and several forms of
renal disease have been associated with this widespread use. The hemodynamic actions of …

Cocaine is abused worldwide as a recreational drug. It is a potent activator of the
sympathetic nervous system leading to intense vasoconstriction, endothelial dysfunction …

Cocaine abuse continues to be prevalent and effective therapies for cocaine craving and
addiction remain elusive. In the last decade immunopharmacotherapy has been proposed …