Summary That uncoupling protein 1 (UCP1) is the sole mediator of adipocyte thermogenesis
is a conventional viewpoint that has primarily been inferred from the attenuation of the …

As one of the main pathogenic factors of cardiovascular and cerebrovascular diseases, the
incidence of metabolic diseases such as adiposity and metabolic dysfunction-associated …

Inhibiting glycogen synthase kinase 3 (GSK3) improves muscle function, metabolism, and
bone health in many diseases and conditions; however, whether GSK3 should be targeted …

Individuals with metabolic syndrome have a high risk of developing cardiovascular disorders
that is closely tied to visceral adipose tissue dysfunction, as well as an altered interaction …

This protocol employs the indo-1 Ca 2+ fluorophore to quantify Ca 2+ uptake by the sarco
(endo) plasmic reticulum Ca 2+ ATPase pump in murine muscle homogenates and allows …

Context Housing temperature is a critical regulator of mouse metabolism and thermoneutral
housing can improve model translation to humans. However, the impact of housing …

We examined the effects of∼ 30 days of spaceflight on glycogen synthase kinase 3 (GSK3)
content and inhibitory serine phosphorylation in murine muscle and bone samples from four …

In this study we investigated the potential synergistic effects of moderate interval training
(MIT) and lithium on spatial learning and memory. Forty-two male Wistar males were …

Nutraceutical approaches to promote adipose tissue thermogenesis may help to prevent
obesity onset. Creatine is a critical regulator of adipose metabolic function and low-dose …

Circadian desynchronizations are associated with psychiatric disorders as well as with
higher suicidal risk. Brown adipose tissue (BAT) is important in the regulation of body …