Emerging approaches of neural regeneration using physical stimulations solely or coupled with smart piezoelectric nano-biomaterials

I De, P Sharma, M Singh - European Journal of Pharmaceutics and …, 2022 - Elsevier
Neural regeneration is a challenging venture as it is limited by various intrinsic physiological
parameters such as the presence of biomolecules like Nogo-A, Ephrin-B3 and Neurocan …

Physical Stimulation Methods Developed for In Vitro Neuronal Differentiation Studies of PC12 Cells: A Comprehensive Review

K Tominami, T Kudo, T Noguchi, Y Hayashi… - International Journal of …, 2024 - mdpi.com
PC12 cells, which are derived from rat adrenal pheochromocytoma cells, are widely used for
the study of neuronal differentiation. NGF induces neuronal differentiation in PC12 cells by …

Histologic and clinical changes in vulvovaginal tissue after treatment with a transcutaneous temperature-controlled radiofrequency device

MJV Wilson, J Bolton, IT Jones, DC Wu… - Dermatologic …, 2018 - journals.lww.com
BACKGROUND Although transcutaneous temperature-controlled radiofrequency (TTCRF)
may effectively treat vulvovaginal laxity (VVL), atrophic vaginitis (AV), orgasmic dysfunction …

The efficacy and safety of a combined multipolar radiofrequency with pulsed electromagnetic field technology for the treatment of vaginal laxity: a double-blinded …

P Wattanakrai, N Limpjaroenviriyakul… - Lasers in Medical …, 2022 - Springer
Non-invasive vaginal rejuvenation with radiofrequency (RF) and lasers devices have gained
popularity, but well-designed studies confirming their effectiveness are lacking. The aim of …

Implication of thermal signaling in neuronal differentiation revealed by manipulation and measurement of intracellular temperature

S Chuma, K Kiyosue, T Akiyama, M Kinoshita… - Nature …, 2024 - nature.com
Neuronal differentiation—the development of neurons from neural stem cells—involves
neurite outgrowth and is a key process during the development and regeneration of neural …

Neuroglobin boosts axon regeneration during ischemic reperfusion via p38 binding and activation depending on oxygen signal

XX Xiong, F Pan, RQ Chen, DX Hu, XY Qiu, CY Li… - Cell death & …, 2018 - nature.com
Cerebral ischemia causes severe cell death or injury including axon breakdown or retraction
in the brain. Axon regeneration is crucial for the functional recovery of injured neurons or …

NGF-Induced Nav1. 7 upregulation contributes to chronic post-surgical pain by activating SGK1-dependent Nedd4-2 phosphorylation

BW Liu, J Zhang, YS Hong, NB Li, Y Liu, M Zhang… - Molecular …, 2021 - Springer
At present, chronic post-surgical pain (CPSP) is difficult to prevent and cure clinically
because of our lack of understanding of its mechanisms. Surgical injury induces the …

SP600125 enhances temperature-controlled repeated thermal stimulation-induced neurite outgrowth in PC12-P1F1 cells

YR Luo, T Kudo, K Tominami, S Izumi… - International Journal of …, 2022 - mdpi.com
This study evaluated the mechanism of temperature-controlled repeated thermal stimulation
(TRTS)-mediated neuronal differentiation. We assessed the effect of SP600125, a c-Jun N …

Prussian blue nanoparticle-mediated scalable thermal stimulation for in vitro neuronal differentiation

S Blasa, M Borzenkov, V Pastori, L Doveri, P Pallavicini… - Nanomaterials, 2022 - mdpi.com
Heating has recently been applied as an alternative to electrical stimulation to modulate
excitability and to induce neuritogenesis and the expression of neuronal markers; however …

Customised spatiotemporal temperature gradients created by a liquid metal enabled vortex generator

JY Zhu, P Thurgood, N Nguyen, K Ghorbani… - Lab on a Chip, 2017 - pubs.rsc.org
Generating customised temperature gradients in miniaturised flow-free liquid chambers is
challenging due to the dominance of diffusion. Inducing internal flows in the form of vortices …