Ovarian cancer is the seventh most common gynaecologic malignancy seen in women.
Majority of the patients with ovarian cancer are diagnosed at the advanced stage making …

Introduction: Oral and oropharyngeal squamous cell carcinoma (OSCC and OPSCC)
represents an increasing problem in the global public health. Indeed, squamous cell …

Background Various types of cancer therapy strategies have been investigated and
successfully applied so far. There are a few modern strategies for improving drug selectivity …

DNA has represented the most exploited target for the development of anticancer agents. It
is now established that DNA may assume a variety of non-B conformations. This evidence …

Transcription factors of the nuclear factor κB (NF-κB) family are central coordinating
regulators of the host defence responses to stress, injury and infection. Aberrant NF-κB …

Abstract Background Long non-coding RNAs (LncRNAs) utilize a wide variety of
mechanisms to regulate RNAs or proteins on the transcriptional or post-transcriptional …

The VEGFR-2/AKT pathway is a crucial axis in tumor survival where it is highly dysregulated
in many cancer types. In this research, novel coumarin-acid hydrazides were synthesized …

Here, we determined the anti-neoplastic actions of formononetin (FT) against multiple
myeloma (MM) and elucidated its possible mode of action. It was observed that FT …

Prostate cancer is the most prevalent malignant tumor in men across developed countries.
Traditional diagnostic and therapeutic methods for this tumor have become increasingly …

Staurosporine, which is an inhibitor of a broad spectrum of protein kinases, has shown
cytotoxicity on several human cancer cells. However, the underlying mechanism is not well …