Computational system level approaches for discerning reciprocal regulation of IL10 and IL12 in leishmaniasis
S Khandibharad, S Singh - Frontiers in Genetics, 2022 - frontiersin.org
IL12 and IL10 are two of the major cytokines which control the fate of Leishmaniasis. This
paper presents two models healthy state and diseased state which shows how secretion of …
paper presents two models healthy state and diseased state which shows how secretion of …
Application of sensitivity analysis to discover potential molecular drug targets
M Kardynska, J Smieja, P Paszek… - International Journal of …, 2022 - mdpi.com
Mathematical modeling of signaling pathways and regulatory networks has been supporting
experimental research for some time now. Sensitivity analysis, aimed at finding model …
experimental research for some time now. Sensitivity analysis, aimed at finding model …
MicroRNA‐520c‐3p impacts sphingolipid metabolism mediating PI3K/AKT signaling in NSCLC: Systems perspective
P Gulhane, S Singh - Journal of Cellular Biochemistry, 2022 - Wiley Online Library
Increasing research suggests that sphingolipid metabolism is essential for the progression
and metastasis of cancer. The underlying mechanistic insight into the dysregulation of …
and metastasis of cancer. The underlying mechanistic insight into the dysregulation of …
Automatic control and feedback loops in biology and medicine
J Smieja - Automation 2019: Progress in Automation, Robotics …, 2020 - Springer
Biological systems, from individual cells to cells populations, to tissue and organs to whole
organisms, are equipped in multiple positive and negative feedback control mechanisms …
organisms, are equipped in multiple positive and negative feedback control mechanisms …