Antibiotic-induced cell chaining triggers pneumococcal competence by reshaping quorum sensing to autocrine-like signaling
A Domenech, J Slager, JW Veening - Cell reports, 2018 - cell.com
Streptococcus pneumoniae can acquire antibiotic resistance by activation of competence
and subsequent DNA uptake. Here, we demonstrate that aztreonam (ATM) and clavulanic …
and subsequent DNA uptake. Here, we demonstrate that aztreonam (ATM) and clavulanic …
Rgg-Shp regulators are important for pneumococcal colonization and invasion through their effect on mannose utilization and capsule synthesis
Microbes communicate with each other by using quorum sensing (QS) systems and
modulate their collective 'behavior'for in-host colonization and virulence, biofilm formation …
modulate their collective 'behavior'for in-host colonization and virulence, biofilm formation …
Pneumococcal galactose catabolism is controlled by multiple regulators acting on pyruvate formate lyase
Catabolism of galactose by Streptococcus pneumoniae alters the microbe's metabolism from
homolactic to mixed acid fermentation, and this shift is linked to the microbe's virulence …
homolactic to mixed acid fermentation, and this shift is linked to the microbe's virulence …
TprA/PhrA quorum sensing system has a major effect on pneumococcal survival in respiratory tract and blood, and its activity is controlled by CcpA and GlnR
Streptococcus pneumoniae is able to cause deadly diseases by infecting different tissues,
each with distinct environmental and nutritional compositions. We hypothesize that the …
each with distinct environmental and nutritional compositions. We hypothesize that the …
Niacin-mediated Gene Expression and Role of NiaR as a Transcriptional Repressor of niaX, nadC, and pnuC in Streptococcus pneumoniae
NAD (Nicotinamide Adenine Dinucleotide) biosynthesis is vital for bacterial physiology and
plays an important role in cellular metabolism. A naturally occurring vitamin B complex …
plays an important role in cellular metabolism. A naturally occurring vitamin B complex …
Maltose-Dependent Transcriptional Regulation of the mal Regulon by MalR in Streptococcus pneumoniae
The maltose regulon (mal regulon) has previously been shown to consist of the mal gene
cluster (malMP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study …
cluster (malMP, malXCD and malAR operons) in Streptococcus pneumoniae. In this study …
Phosphosugar Stress in Bacillus subtilis: Intracellular Accumulation of Mannose 6-Phosphate Derepressed the glcR-phoC Operon from Repression by GlcR
K Morabbi Heravi, I Manzoor, H Watzlawick… - Journal of …, 2019 - Am Soc Microbiol
Bacillus subtilis phosphorylates sugars during or after their transport into the cell.
Perturbation in the conversion of intracellular phosphosugars to the central carbon …
Perturbation in the conversion of intracellular phosphosugars to the central carbon …
Ni2+-Dependent and PsaR-Mediated Regulation of the Virulence Genes pcpA, psaBCA, and prtA in Streptococcus pneumoniae
Previous studies have shown that the transcriptional regulator PsaR regulates the
expression of the PsaR regulon consisting of genes encoding choline binding protein …
expression of the PsaR regulon consisting of genes encoding choline binding protein …
GalR acts as a transcriptional activator of galKT in the presence of galactose in Streptococcus pneumoniae
We explored the regulatory mechanism of Leloir pathway genes in Streptococcus
pneumoniae D39. Here, we demonstrate that the expression of galKT is galactose …
pneumoniae D39. Here, we demonstrate that the expression of galKT is galactose …
Co2+-dependent gene expression in Streptococcus pneumoniae: opposite effect of Mn2+ and Co2+ on the expression of the virulence genes psaBCA, pcpA, and prtA
Manganese (Mn2+)-, zinc (Zn2+)-and copper (Cu2+) play significant roles in transcriptional
gene regulation, physiology, and virulence of Streptococcus pneumoniae. So far, the effect …
gene regulation, physiology, and virulence of Streptococcus pneumoniae. So far, the effect …