A hallmark of α-synucleinopathies (eg, Parkinson's disease) is the misfolding and
aggregation of α-synuclein in tissues and biological fluids. Protein amplification assays like …

Medical science has made revolutionary discoveries around the nosology and aetiology of
the neurodegenerative diseases. Dementia is the second leading cause of death in …

Blood-based biomarkers for motor neuron disease are needed for better diagnosis,
progression prediction, and clinical trial monitoring. We used whole blood-derived total RNA …

Pathological proteins in amyotrophic lateral sclerosis (ALS), such as superoxide dismutase
1, TAR DNA-binding protein 43, and fused in sarcoma, exhibit a prion-like pattern. All these …

A hallmark of α-synucleinopathies including Parkinson's disease, dementia with Lewy
bodies, and multiple system atrophy, is the misfolding and aggregation of α-synuclein in …