Quaternary ammonium compounds: a chemical class of emerging concern

WA Arnold, A Blum, J Branyan, TA Bruton… - … science & technology, 2023 - ACS Publications
Quaternary ammonium compounds (QACs), a large class of chemicals that includes high
production volume substances, have been used for decades as antimicrobials …

[HTML][HTML] Risks of benzalkonium chlorides as emerging contaminants in the environment and possible control strategies from the perspective of ecopharmacovigilance

M Liao, S Wei, J Zhao, J Wang, G Fan - Ecotoxicology and Environmental …, 2023 - Elsevier
An unprecedented increase in the use of disinfection products triggered by the coronavirus
disease 2019 (COVID-19) pandemic is resulting in aggravating environmental loads of …

Beneficial or harmful: Time-dependent hormesis induced by typical disinfectants and their mixtures with toxicological interaction

MT Tao, SS Liu, ZW Gu, TT Ding, P Huang - Science of The Total …, 2023 - Elsevier
Disinfectants and their mixtures can induce hormesis. However, how the mixture hormesis is
related to those of components and the interactions in disinfectant mixtures remain unclear …

Novel scaffold based graphene oxide doped electrospun iota carrageenan/polyvinyl alcohol for wound healing and pathogen reduction: In-vitro and in-vivo study

MH Gouda, SM Ali, SS Othman, S A. Abd Al-Aziz… - Scientific Reports, 2021 - nature.com
Wound healing is a complicated multicellular process that involves several kinds of cells
including macrophages, fibroblasts, endothelial cells, keratinocytes and platelets that are …

A fish perspective on SARS-CoV-2: Toxicity of benzalkonium chloride on Danio rerio

B Sousa, I Domingues, B Nunes - Environmental Toxicology and …, 2023 - Elsevier
SARS-CoV-2 outbreak led to an increased marketing of disinfectants, creating a potential
environmental problem. For instance, pre-pandemic environmental levels of the disinfectant …

The history of surfactants and review of their allergic and irritant properties

CL Presley, M Militello, C Barber, R Ladd, M Laughter… - Dermatitis, 2021 - liebertpub.com
Surfactants, many of which are used as detergents, can be found in many common
household items, such as shampoos, conditioners, soaps, and cosmetics. One should …

Benzalkonium chloride and cetylpyridinium chloride induce apoptosis in human lung epithelial cells and alter surface activity of pulmonary surfactant monolayers

S Kanno, S Hirano, H Kato, M Fukuta, T Mukai… - Chemico-Biological …, 2020 - Elsevier
Quaternary ammonium compounds (eg, benzalkonium chloride (BAC) and cetylpyridinium
chloride (CPC)) constitute a group of cationic surfactants are widely used for personal …

Cryomilled electrospun nanofiber mats containing d-mannitol exhibit suitable for aerosol delivery of proteins

T Ito, S Tamashiro, H Okuda, E Yamazoe… - International Journal of …, 2024 - Elsevier
Dry powder inhalers (DPIs) are the first choice for inhalation drug development. However,
some conventional DPI formulation processes require heating, which may damage high …

The Antibacterial Effects of New N-Alkylpyridinium Salts on Planktonic and Biofilm Bacteria

M Hympanova, S Terlep, A Markova, L Prchal… - Frontiers in …, 2020 - frontiersin.org
An increasing microbial resistance to known antibiotics raises a demand for new
antimicrobials. In this study the antimicrobial properties of a series of new N-Alkylpyridinium …

Topical effect of benzalkonium bromide on wound healing and potential cellular and molecular mechanisms

J Zhang, Y Yan, Y Li, C Shen… - International Wound …, 2021 - Wiley Online Library
Benzalkonium bromide (BB) has been widely used as a skin antiseptic for wound
management. However, BB had proinflammation and reactive oxygen species (ROS) …