Computational modelling of mechano-electric feedback and its arrhythmogenic effects in human ventricular models

Y Lee, B Cansız, M Kaliske - Computer Methods in Biomechanics …, 2022 - Taylor & Francis
The current study aims to investigate the role of mechano-electric feedback (MEF) in healthy
cardiac cycles and in cardiac arrhythmia using human ventricular models. The numerical …

How viscous is the beating heart? Insights from a computational study

OZ Tikenoğulları, FS Costabal, J Yao, A Marsden… - Computational …, 2022 - Springer
Understanding tissue rheology is critical to accurately model the human heart. While the
elastic properties of cardiac tissue have been extensively studied, its viscous properties …

A multiphysical computational model of myocardial growth adopted to human pathological ventricular remodelling

Y Lee, B Cansız, M Kaliske - Computational Mechanics, 2023 - Springer
We present a novel three-dimensional constitutive model that describes an electro-visco-
elastic-growth response on the myocardium with a fully implicit staggered solution …

Efficient dynamic modeling of soft tissue deformation using a WSC-integrated order reduction method

W Hou, J Xiong, Z Xia - Journal of Computational Science, 2023 - Elsevier
Abstract Background and Objectives: Computational modeling of soft tissue deformation is a
fundamental issue for engineering assistive medical procedures. However, existing methods …

Fast and reliable reduced‐order models for cardiac electrophysiology

S Chellappa, B Cansız, L Feng, P Benner… - GAMM …, 2023 - Wiley Online Library
Mathematical models of the human heart increasingly play a vital role in understanding the
working mechanisms of the heart, both under healthy functioning and during disease. The …

A simple phenomenological approach for myocardial contraction: formulation, parameter sensitivity study and applications in organ level simulations

B Cansız, LA Woodworth, M Kaliske - Mechanics of Soft Materials, 2021 - Springer
Contraction in myocardial tissue is the result of a complex process through which chemical
energy on the cellular level is converted into the mechanical energy needed to circulate …

[HTML][HTML] A comparative study of fully implicit staggered and monolithic solution methods. Part II: Coupled excitation–contraction equations of cardiac electromechanics

B Cansız, M Kaliske - Journal of Computational and Applied Mathematics, 2024 - Elsevier
A comparative study of fully implicit staggered and monolithic solution algorithms for the
coupled bidomain equations of cardiac electrophysiology was discussed in Part I (JCAM …

A comparative study of fully implicit staggered and monolithic solution methods. Part I: Coupled bidomain equations of cardiac electrophysiology

B Cansız, M Kaliske - Journal of Computational and Applied Mathematics, 2022 - Elsevier
This manuscript presents an extensive comparative analysis between a staggered and a
monolithic solution technique for the bidomain equations of cardiac electrophysiology in the …

Assessment of LV structural remodelling by the application of the finite element method to 3D echocardiography data

Y Lee, B Cansız, K Sveric, A Linke… - Computer Methods in …, 2024 - Taylor & Francis
This study presents novel applications for conducting left ventricular (LV) shape analysis
within a finite element (FE) framework. The 3D endocardial surface data of both healthy and …

A new approach for analysing motion and deformation of left ventricle: Post‐processing 3D echocardiography data with finite element method

B Cansız, K Sveric, A Linke, M Kaliske - PAMM, 2023 - Wiley Online Library
In the medical community, it is common practice to examine segmental (regional) values. For
instance, echocardiography data are analysed by dividing the left ventricle (LV) endocardial …