Cell of all trades: oligodendrocyte precursor cells in synaptic, vascular, and immune function

LA Akay, AH Effenberger, LH Tsai - Genes & development, 2021 - genesdev.cshlp.org
Oligodendrocyte precursor cells (OPCs) are not merely a transitory progenitor cell type, but
rather a distinct and heterogeneous population of glia with various functions in the …

Revisiting the roles of progesterone and allopregnanolone in the nervous system: resurgence of the progesterone receptors

M Schumacher, C Mattern, A Ghoumari… - Progress in …, 2014 - Elsevier
Progesterone is commonly considered as a female reproductive hormone and is well-known
for its role in pregnancy. It is less well appreciated that progesterone and its metabolite …

Progesterone and allopregnanolone in the central nervous system: response to injury and implication for neuroprotection

R Guennoun, F Labombarda, MCG Deniselle… - The Journal of steroid …, 2015 - Elsevier
Progesterone is a well-known steroid hormone, synthesized by ovaries and placenta in
females, and by adrenal glands in both males and females. Several tissues are targets of …

Progesterone synthesis in the nervous system: implications for myelination and myelin repair

M Schumacher, R Hussain, N Gago… - Frontiers in …, 2012 - frontiersin.org
Progesterone is well known as a female reproductive hormone and in particular for its role in
uterine receptivity, implantation, and the maintenance of pregnancy. However …

A systematic review of non-invasive pharmacologic neuroprotective treatments for acute spinal cord injury

BK Kwon, E Okon, J Hillyer, C Mann… - Journal of …, 2011 - liebertpub.com
An increasing number of therapies for spinal cord injury (SCI) are emerging from the
laboratory and seeking translation into human clinical trials. Many of these are administered …

Progesterone actions during central nervous system development

JC González-Orozco, I Camacho-Arroyo - Frontiers in neuroscience, 2019 - frontiersin.org
Although progesterone is a steroid hormone mainly associated with female reproductive
functions, such as uterine receptivity and maintenance of pregnancy, accumulating data …

Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions

RC Melcangi, S Giatti, D Calabrese, M Pesaresi… - Progress in …, 2014 - Elsevier
Progesterone is synthesized and actively metabolized in the central and peripheral nervous
system, into neuroactive steroid metabolites, such as dihydroprogesterone …

Progesterone neuroprotection in traumatic CNS injury and motoneuron degeneration

AF De Nicola, F Labombarda, MCG Deniselle… - Frontiers in …, 2009 - Elsevier
Studies on the neuroprotective and promyelinating effects of progesterone in the nervous
system are of great interest due to their potential clinical connotations. In peripheral …

Progestogen-mediated neuroprotection in central nervous system disorders

TB Bassani, CS Bartolomeo, RB Oliveira… - …, 2023 - karger.com
Neuroactive steroids can be synthetic or endogenous molecules produced by neuronal and
glial cells and peripheral glands. Examples include estrogens, testosterone, progesterone …

Progesterone's role in neuroprotection, a review of the evidence

ER Deutsch, TR Espinoza, F Atif, E Woodall, J Kaylor… - Brain research, 2013 - Elsevier
The sex hormone progesterone has been shown to improve outcomes in animal models of a
number of neurologic diseases, including traumatic brain injury, ischemia, spinal cord injury …